PREGABALIN

This study looks at whether adding esketamine to standard fibromyalgia treatments can reduce pain more quickly and effectively. About 92 adults with fibromyalgia who haven't gotten enough relief from other treatments will take part. Researchers will compare pain levels between th…

This study compares two medications, pregabalin and mirogabalin, to see which works better for easing fibromyalgia pain. About 674 adults with moderate to severe fibromyalgia will take one of the drugs and report their pain levels. The goal is to find a more effective and safer t…

This study compares pregabalin alone versus pregabalin plus dexmedetomidine for treating fibromyalgia, a condition causing widespread pain and fatigue. Researchers want to see if the combination provides better pain relief without more side effects. The trial will enroll 400 adul…

This study compares taking pregabalin alone versus pregabalin plus venlafaxine for fibromyalgia, a condition causing widespread pain and fatigue. Researchers want to see if the combination provides better pain relief without more side effects. The study will enroll 750 adults wit…

This study compares taking pregabalin alone versus pregabalin plus desvenlafaxine for fibromyalgia pain. Fibromyalgia causes widespread pain and fatigue, and current treatments only help about 25-40% of patients. Researchers want to see if the combination provides better pain rel…

This study tests whether adding amantadine or duloxetine to the standard painkiller pregabalin can prevent chronic pain after mastectomy. About 150 women undergoing breast cancer surgery will be randomly assigned to one of three drug combinations. The goal is to see if these add-…

This study tests a new drug called Y-4 for people with long-term nerve pain after shingles (postherpetic neuralgia). About 160 adults will take either Y-4 or the standard drug pregabalin for 14 weeks. Researchers will check if Y-4 reduces daily pain better and is safe to use.

This study compares taking pregabalin alone versus combining it with another drug (toludesvenlafaxine) to treat fibromyalgia, a condition causing widespread pain and fatigue. Researchers aim to see if the combination provides better pain relief without more side effects. About 38…

This study tests two medications, pregabalin and a newer drug called crisugabalin, to see which works better for fibromyalgia pain. Fibromyalgia causes widespread pain, fatigue, and mood issues, and current treatments only help about 25-40% of patients. The trial will enroll over…

This study tests whether melatonin (a natural sleep hormone) works as well as pregabalin (a nerve pain drug) for managing pain and anxiety after spine surgery. About 105 adults aged 21-60 having elective spine surgery will receive one of the two medicines right after surgery. Res…