PAIN, CHRONIC
Clinical trials for PAIN, CHRONIC explained in plain language.
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Brain scans reveal hidden inflammation in back pain - can an old antibiotic help?
Disease control CompletedThis study aimed to see if brain and spinal cord inflammation is linked to chronic low back pain. Researchers used advanced brain scans on 60 patients to measure this inflammation. They also tested whether a two-week course of the drug minocycline could reduce both the inflammati…
Matched conditions: PAIN, CHRONIC
Phase: PHASE2 • Sponsor: Marco Loggia • Aim: Disease control
Last updated Mar 19, 2026 14:55 UTC
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New toolkit aims to help workers in pain stay productive
Symptom relief CompletedThis study tested a 'Pain at Work' toolkit designed to help employees with chronic pain better manage their condition while on the job. Researchers wanted to see if the toolkit, sometimes paired with therapist phone calls, was practical and acceptable for workplaces and employees…
Matched conditions: PAIN, CHRONIC
Phase: NA • Sponsor: University of Nottingham • Aim: Symptom relief
Last updated Apr 01, 2026 21:41 UTC
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Massage guns and step tracking: new hope for older women in pain?
Symptom relief CompletedThis study tested whether having older women track their daily physical activity, their use of a massage gun, or both, would help them stick with these pain-management strategies. Researchers enrolled 108 women aged 65+ who reported chronic pain as a barrier to being active. The …
Matched conditions: PAIN, CHRONIC
Phase: NA • Sponsor: University of Michigan • Aim: Symptom relief
Last updated Apr 01, 2026 21:41 UTC
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New Hands-On therapy tested to ease chronic pain and curb opioid use
Symptom relief CompletedThis study tested whether a hands-on therapy called myoActivation could help adults with chronic pain, especially those also struggling with opioid use. Researchers followed 41 patients from a community pain clinic to see if the therapy reduced their pain, improved their daily fu…
Matched conditions: PAIN, CHRONIC
Sponsor: University of British Columbia • Aim: Symptom relief
Last updated Apr 01, 2026 14:41 UTC
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Can a simple chat before surgery ease your pain and fear?
Symptom relief CompletedThis study tested whether providing education about pain and a pre-surgery check-up could help reduce anxiety, stress, and pain for women undergoing a planned hysterectomy. Researchers worked with 62 women having this surgery at a hospital in Mexico. They compared outcomes betwee…
Matched conditions: PAIN, CHRONIC
Phase: NA • Sponsor: Instituto Neurociencia Del Dolor • Aim: Symptom relief
Last updated Mar 31, 2026 12:12 UTC
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New Mind-Body program aims to tame chronic back pain
Symptom relief CompletedThis study tested whether a comprehensive program could help people with long-term, unexplained low back pain. Seventy adults participated in a supervised program combining exercise, education, mindfulness, and behavior change techniques. Researchers measured changes in pain, phy…
Matched conditions: PAIN, CHRONIC
Phase: NA • Sponsor: IBS Granada • Aim: Symptom relief
Last updated Mar 31, 2026 12:11 UTC
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Mind over pain: can talk therapy ease recovery after a broken bone?
Symptom relief CompletedThis study tested whether a type of talk therapy called cognitive behavioral therapy (CBT) could help reduce long-term pain after surgery for a broken arm or leg. Over 1,000 adults who had surgery for a fracture received either CBT or standard care. The goal was to see if changin…
Matched conditions: PAIN, CHRONIC
Phase: NA • Sponsor: McMaster University • Aim: Symptom relief
Last updated Mar 31, 2026 12:11 UTC
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Shock waves vs. nerve zaps: the battle for heel pain relief
Symptom relief CompletedThis study compared two non-invasive treatments for chronic pain caused by heel spurs. It tested a newer nerve stimulation method against a more established shock wave therapy. The goal was to see which one was better at reducing pain and improving foot function for patients.
Matched conditions: PAIN, CHRONIC
Phase: NA • Sponsor: Halil Ibrahim Altun • Aim: Symptom relief
Last updated Mar 30, 2026 14:33 UTC
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Muscle relaxant pill tested to boost spinal anesthesia for surgery pain
Symptom relief CompletedThis study tested if taking an oral muscle relaxant (tizanidine) before surgery improves pain relief when combined with standard spinal anesthesia (levobupivacaine) for leg operations. It involved 64 adults having planned lower limb surgeries lasting under 2.5 hours. Researchers …
Matched conditions: PAIN, CHRONIC
Phase: PHASE4 • Sponsor: All India Institute of Medical Sciences • Aim: Symptom relief
Last updated Mar 30, 2026 14:32 UTC
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Tiny plug offers hope for Women's chronic pelvic pain
Symptom relief CompletedThis study looked at a minimally invasive procedure called plug embolization to treat chronic pelvic pain in women with Pelvic Congestion Syndrome. Doctors inserted a small plug into enlarged pelvic veins to block them, aiming to reduce pain and improve quality of life. The study…
Matched conditions: PAIN, CHRONIC
Sponsor: Halil Ibrahim Altun • Aim: Symptom relief
Last updated Mar 30, 2026 14:31 UTC
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Common pain pill vs simple exercises: which works better for wrist pain?
Symptom relief CompletedThis study tested whether over-the-counter ibuprofen or specific nerve gliding exercises work better than no treatment for carpal tunnel syndrome. Researchers compared pain levels and hand function in 123 people with confirmed carpal tunnel. Participants were randomly assigned to…
Matched conditions: PAIN, CHRONIC
Phase: PHASE4 • Sponsor: Universidad Europea de Madrid • Aim: Symptom relief
Last updated Mar 30, 2026 14:30 UTC
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Ancient exercise meets modern tech: can virtual tai chi help veterans heal?
Symptom relief CompletedThis study tested whether it's practical to run a future, larger trial comparing two remote programs for veterans. 42 veterans with PTSD and long-term pain were assigned to either a 12-week Tai Chi class or a general wellness class, both delivered over video. The main goal was to…
Matched conditions: PAIN, CHRONIC
Phase: NA • Sponsor: Boston University • Aim: Symptom relief
Last updated Mar 25, 2026 14:08 UTC
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Sedation for back pain shots: does it help or hinder?
Symptom relief CompletedThis study looked back at 201 patients who received steroid injections for chronic low back pain from a herniated disc. It compared patients who received sedation during the procedure to those who did not. The goal was to see if sedation affected pain relief, patient satisfaction…
Matched conditions: PAIN, CHRONIC
Sponsor: Kanuni Sultan Suleyman Training and Research Hospital • Aim: Symptom relief
Last updated Mar 23, 2026 15:17 UTC
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Can a sleep app ease the pain? new study investigates
Symptom relief CompletedThis study tested whether adding a smartphone app that delivers cognitive-behavioral therapy for insomnia (CBT-I) to a standard 4-week inpatient rehabilitation program helps people who have both chronic pain and sleep problems. 105 participants with musculoskeletal pain and insom…
Matched conditions: PAIN, CHRONIC
Phase: NA • Sponsor: Norwegian University of Science and Technology • Aim: Symptom relief
Last updated Mar 18, 2026 14:41 UTC
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New tool measures how patients think about their chronic pain
Knowledge-focused CompletedThis study aimed to validate a French version of a questionnaire that measures whether chronic pain patients believe their pain involves physical, psychological, and social factors. Researchers gave the new questionnaire to 80 French-speaking adults with chronic pain to see if it…
Matched conditions: PAIN, CHRONIC
Sponsor: Benno Rehberg-Klug • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:41 UTC
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Scientists hunt for your Pain's genetic fingerprint to match the perfect treatment
Knowledge-focused CompletedThis study aimed to discover genetic markers that could predict which physical therapy treatments work best for chronic shoulder and muscle pain. Researchers tested three common treatments—laser therapy, ultrasound, and a sugar-water injection—on 80 patients. By analyzing patient…
Matched conditions: PAIN, CHRONIC
Phase: NA • Sponsor: National Taiwan University Hospital • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:28 UTC
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First-of-its-Kind study sheds light on hidden pain in liver disease patients
Knowledge-focused CompletedThis study aimed to find out how common pain is for people with liver cirrhosis who are in the hospital. Researchers asked 30 hospitalized patients about their pain, its location, intensity, and how it affects their sleep and quality of life. The goal was to gather basic informat…
Matched conditions: PAIN, CHRONIC
Sponsor: Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer • Aim: Knowledge-focused
Last updated Mar 25, 2026 14:08 UTC
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Finger clip may tell doctors if your pain shot will work
Knowledge-focused CompletedThis study tested whether a simple finger sensor, which measures blood flow, could predict how well a specific nerve block would relieve chronic neck and arm pain. Researchers gave the nerve block to 92 people with chronic pain from pinched nerves in their neck. They checked if t…
Matched conditions: PAIN, CHRONIC
Sponsor: Keimyung University Dongsan Medical Center • Aim: Knowledge-focused
Last updated Mar 24, 2026 12:02 UTC