PAIN, CHRONIC

This study tested a 12-month telephone-based nurse care program for 805 adults with depression and signs of opioid use disorder. Participants were randomly assigned to receive nurse support or usual care. The goal was to see if the program could improve treatment for opioid use a…

This study tested a new pain self-management program called COPES against standard cognitive behavioral therapy for chronic pain in 764 veterans. The goal was to see if COPES could better reduce how much pain interferes with daily life. Participants had chronic musculoskeletal pa…

This study tested a program called PRIME for older women with chronic pain and depression who also have physical disabilities. Nine women took part in nurse-led goal-setting visits and group therapy sessions focused on acceptance and commitment. The goal was to see if this combin…

This study tested a resilience coaching program (PRISM) for 260 teens aged 12-17 with chronic musculoskeletal pain. The goal was to see if coaching improves daily function, reduces distress, and lessens pain compared to usual care. Participants completed surveys and coaching sess…

This study compared telemedicine follow-ups to standard in-person clinic visits for cancer patients with chronic pain. Researchers measured how much pain interfered with daily activities using a standard questionnaire. The goal was to see if remote care could be as effective and …

This study compared two methods of pain relief after hip replacement surgery: a newer technique called erector spinae plane block (ESPB) and the standard epidural. 60 adults having hip replacement took part. Researchers measured pain levels, opioid use, muscle strength, and walki…

This study tested a one-day educational workshop for people with chronic non-cancer pain who take high doses of opioids. The workshop, led by a team of doctors, psychologists, and pharmacists, provided information on opioid risks and taught coping strategies. Researchers wanted t…

This completed study tested two versions of a cooled radiofrequency procedure to relieve chronic knee pain from osteoarthritis. Ten adults with moderate to severe pain received either the standard or a revised nerve-targeting technique. Researchers measured pain, knee function, q…

This study tested a new online program that teaches mindfulness and coping skills to people recovering from surgery. The goal was to see if patients find it helpful and easy to use compared to a workshop led by a psychologist. 68 adults who had surgery and were referred to a pain…

This completed study looked at how well radiofrequency ablation (a procedure that uses heat to calm pain nerves) works for people with chronic pain. 298 participants were treated with a Boston Scientific device and then rated their improvement. The goal was to see real-world resu…

This completed study tested two multimodal programs in 70 adults with non-specific chronic low back pain. Both programs combined exercise, behaviour change, education, and mindfulness; one also added functional resistance training. The goal was to see if these approaches improve …

This study tested if an app that teaches better sleep habits could help people with long-term pain and insomnia. 105 adults in a 4-week rehab program either got the app or standard care. The goal was to see if the app improved sleep quality more than rehab alone.

This study tested a procedure called endovascular plug embolization to treat chronic pelvic pain caused by Pelvic Congestion Syndrome (PCS), a condition where veins in the pelvis become enlarged and painful. 44 women with PCS took part. The procedure uses a small plug to block th…

This study tested whether taking a pill called tizanidine before spinal anesthesia (levobupivacaine) improves pain control during and after lower leg surgery. Sixty-four adults scheduled for elective leg surgery were randomly assigned to receive either the standard spinal injecti…

This study looked at whether teaching patients about pain before a planned hysterectomy (removal of the uterus) could help lower their anxiety, stress, and pain after surgery. 62 adults took part and received either standard care or extra education about pain. The goal was to see…

This study tested whether a toolkit called Pain at Work (PAW) can help employees with chronic pain manage their symptoms and stay productive. Around 380 workers from different workplaces in England took part, with some using the toolkit plus support calls and others receiving usu…

This study tested two common treatments for carpal tunnel syndrome: over-the-counter ibuprofen pills and a nerve exercise called neural mobilization. 123 adults with carpal tunnel took part. The goal was to see if these treatments reduce pain and improve hand and arm function bet…

This study looked at whether self-monitoring physical activity and using a massage gun can reduce chronic pain in women aged 65 and older. 108 participants tracked their steps and massage use to see which habits best improved pain. The goal was to find simple, effective ways for …

This study compared two noninvasive treatments for chronic heel pain caused by heel spurs: extracorporeal shock wave therapy and a newer nerve stimulation method called transcutaneous pulsed radiofrequency. 100 adults aged 18-65 with heel spurs took part. The goal was to see whic…

This pilot study tested a non-drug treatment called myoActivation for chronic pain in 41 marginalized people. The therapy uses a structured assessment and needling to release muscle tension. Researchers measured pain, function, and quality of life over 24 weeks to see if it helps…

This study tested whether cognitive behavioral therapy (CBT) can reduce persistent pain after fracture surgery. Over 1,000 adults with broken arm or leg bones received either CBT or usual care. The goal was to see if CBT lowers the number of people who still have moderate to seve…

This completed study looked at how often hospitalized patients with cirrhosis experience pain. Researchers asked 30 patients about their pain, its location, intensity, and whether it was chronic. The goal was to highlight an often-overlooked issue and encourage better pain care f…

This study aimed to develop and test two new questionnaires for people with recurrent urinary tract infections (UTIs). The Recurrent UTI Symptom Scale measures symptom severity, while the Recurrent UTI Impact Questionnaire looks at how the condition affects daily life, work, and …

This study tested whether offering tai chi classes online is a practical way to help veterans with PTSD and chronic pain. Researchers worked with 42 veterans to see if they would attend sessions and find the program satisfactory. The goal was to gather information needed to desig…

This study looked at how to better diagnose chronic pain in 100 torture survivors. Researchers tested a simple pain questionnaire to see if it could find pain that standard methods miss. They also interviewed survivors about pain treatments and tested whether a digital program co…

This study tested a French version of a questionnaire that measures how people with chronic pain think about their condition. Researchers compared it to another questionnaire about pain self-confidence. The goal was to see if the new scale adds useful information beyond existing …

This study used special brain scans to look for signs of inflammation in the brains and spinal cords of 60 people with chronic low back pain. Researchers also tested whether a short course of the antibiotic minocycline could reduce both inflammation and pain. The goal was to bett…

This study reviewed records of 201 adults who received a common back pain injection (transforaminal epidural steroid injection) to see if using sedation made a difference. Researchers compared patient satisfaction, pain scores, radiation exposure, and complication rates between t…

This study looked at 80 people with muscle pain to see if genetics can predict which treatment works best. Participants received laser, ultrasound, or sugar-water injections. Researchers analyzed blood and urine to find markers that could guide personalized pain care in the futur…

This completed study with 92 people tested whether a measure called perfusion index (a way to check blood flow) can predict how well a nerve block (erector spinae plane block) relieves chronic neck pain from conditions like herniated discs or spinal narrowing. Researchers tracked…