New hope for knee pain: cooled radiofrequency targets tested
NCT ID NCT05363241
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This completed study tested two versions of a cooled radiofrequency procedure to relieve chronic knee pain from osteoarthritis. Ten adults with moderate to severe pain received either the standard or a revised nerve-targeting technique. Researchers measured pain, knee function, quality of life, and side effects over six months to see which approach works better.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
cooled radiofrequency procedure
What this could lead to
If successful, this could point toward a more effective, minimally invasive pain relief option for people with knee osteoarthritis who cannot have surgery.
What could go wrong
This is a very small, early study with only 10 participants, so results may not apply to everyone. The procedure carries risks like temporary numbness or discomfort.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Universidade Federal de Alfenas
Alfenas, Minas Gerais, Brazil