New hope for knee pain: cooled radiofrequency targets tested

NCT ID NCT05363241

Completed Symptom relief Sponsor: Universidade Federal de Alfenas Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This completed study tested two versions of a cooled radiofrequency procedure to relieve chronic knee pain from osteoarthritis. Ten adults with moderate to severe pain received either the standard or a revised nerve-targeting technique. Researchers measured pain, knee function, quality of life, and side effects over six months to see which approach works better.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: cooled radiofrequency procedure
What this could lead to: If successful, this could point toward a more effective, minimally invasive pain relief option for people with knee osteoarthritis who cannot have surgery.
What could go wrong: This is a very small, early study with only 10 participants, so results may not apply to everyone. The procedure carries risks like temporary numbness or discomfort.

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Conditions

The condition(s) this trial relates to.

agnosia Chronic Pain chronic pain syndrome osteoarthritis, knee pain agnosia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ANALGESIA OSTEOARTHRITIS, KNEE PAIN, CHRONIC

Contacts and locations

Locations

Universidade Federal de Alfenas

Alfenas, Minas Gerais, Brazil

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