OROPHARYNX CANCER

This study is testing a new approach for people with HPV-related throat cancer who have surgery. Researchers want to see if a simple blood test can identify patients who are unlikely to need follow-up radiation. If the blood test after surgery shows no signs of leftover cancer, p…

This study is testing if a blood test that looks for tiny bits of cancer DNA can help doctors decide which patients need radiation after surgery for HPV-related throat cancer. The goal is to see if some patients can safely delay radiation or receive a shorter course of treatment.…

This study is testing a new, personalized way to plan radiation therapy for throat cancer. The goal is to shrink the area of healthy tissue that gets irradiated, aiming to reduce painful side effects like swallowing problems and taste loss, while still effectively treating the ca…

This study is testing whether doctors can safely lower the radiation dose for people with HPV-linked throat cancer. It uses a special scan partway through treatment to find patients who are responding very well. If the scan looks good, those patients will get less radiation, with…

This study is testing whether a patient navigation program called ENDURE helps people with head and neck cancer start their necessary radiation therapy sooner after surgery. It will compare the new program to the usual way patients are scheduled for treatment. The goal is to see …

This study is testing whether a combination of two drugs, sacituzumab govitecan and cetuximab, can help control advanced head and neck cancer that has come back or spread after initial treatment. It will involve about 40 adults whose cancer has progressed despite standard therapy…

This large study is testing two ideas to improve treatment for certain head and neck cancers. It will see if using a smaller, more precise radiation area and/or adding a drug called ATRA (a form of vitamin A) works better than standard radiation alone. The goal is to better contr…

This study is testing a new personalized treatment for advanced cancers caused by HPV. Doctors take a patient's own immune cells, modify them in a lab to better target the cancer, and infuse them back to try to shrink tumors before standard therapy like chemo or surgery. The goal…

This study is testing a new gene therapy for people with advanced cancers caused by HPV. Doctors take a patient's own immune cells, modify them in a lab to better recognize and attack HPV-infected cancer cells, and then infuse them back into the patient. The goal is to see if thi…

This study is testing a gentler radiation treatment for people with HPV-positive throat cancer who have already had surgery. Researchers want to see if using a lower radiation dose and targeting only the neck (instead of the original tumor site too) works as well as the standard,…

This study is testing a new surgical method for rebuilding the mouth or throat after removing cancer. Surgeons will take a piece of skin and tissue from the groin area (external pudendal flap) to use in the reconstruction, hoping it causes fewer problems at the site where it's ta…

This study aims to find out how common oral HPV infection is in healthy adults over 40 in the Czech Republic. Researchers will enroll 20,000 participants to test a new screening method using gargle samples. The goal is to gather information that could lead to earlier detection of…