OROPHARYNX CANCER
Clinical trials for OROPHARYNX CANCER explained in plain language.
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Mid-treatment PET scan may allow safer, lower radiation for throat cancer
Disease control OngoingThis study is testing whether a PET scan taken partway through radiation treatment can identify patients with HPV-related throat cancer who can safely receive a lower dose of radiation. The goal is to reduce side effects while still controlling the cancer. About 120 adults with s…
Matched conditions: OROPHARYNX CANCER
Phase: NA • Sponsor: Duke University • Aim: Disease control
Last updated Jun 27, 2026 13:06 UTC
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New drug combo aims to boost immune attack on HPV throat cancer before surgery
Disease control OngoingThis phase 2 trial tests whether giving targeted radiation along with two immunotherapy drugs (evorpacept and pembrolizumab) before standard surgery can improve outcomes for people with HPV-related throat cancer. The study enrolls 29 patients with early-stage, resectable disease.…
Matched conditions: OROPHARYNX CANCER
Phase: PHASE2 • Sponsor: University of California, San Diego • Aim: Disease control
Last updated Jun 27, 2026 12:35 UTC
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Tailored radiation beams aim to outsmart aggressive throat cancer
Disease control OngoingThis pilot study tests a personalized radiation plan for people with HPV-related throat cancer that is considered high-risk. Using advanced scans (MRI and PET), doctors adjust the radiation dose to target the most aggressive parts of the tumor. The goal is to see if this approach…
Matched conditions: OROPHARYNX CANCER
Phase: PHASE2 • Sponsor: University of Michigan Rogel Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 12:34 UTC
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Could a Chemo-Immunotherapy cocktail spare head and neck cancer patients from radiation?
Disease control OngoingThis phase 2 trial tests a combination of two chemotherapy drugs (carboplatin and nab-paclitaxel) plus an immunotherapy drug (durvalumab) given before surgery for people with locally advanced head and neck cancer. The goal is to shrink or eliminate the tumor so that radiation—whi…
Matched conditions: OROPHARYNX CANCER
Phase: PHASE2 • Sponsor: UNC Lineberger Comprehensive Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 09:08 UTC
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Immunotherapy may replace chemo in head and neck cancer trial
Disease control OngoingThis study tests whether the immunotherapy drug pembrolizumab (Keytruda) combined with radiation works better than the standard chemotherapy drug cisplatin with radiation for patients with a certain type of head and neck cancer (p16-positive). About 126 adults with advanced or in…
Matched conditions: OROPHARYNX CANCER
Phase: PHASE2 • Sponsor: Loren Mell, MD • Aim: Disease control
Last updated Jun 27, 2026 07:53 UTC
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Natural mouthwash aimed to soothe radiation mouth sores, but study never started
Symptom relief TerminatedThis study planned to test a mouthwash made from copaíba oil, a natural resin, to prevent and treat painful mouth sores (oral mucositis) in people with oral cancer undergoing radiation. The trial was set to include 40 patients, half using the copaíba mouthwash and half a placebo,…
Matched conditions: OROPHARYNX CANCER
Phase: PHASE2 • Sponsor: Instituto Nacional de Cancer, Brazil • Aim: Symptom relief
Last updated Jun 27, 2026 12:05 UTC
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Robotic surgery or radiation? new study compares which is better for throat cancer patients' quality of life
Symptom relief OngoingThis study compares two treatments for early-stage throat cancer: robotic surgery (TORS) or radiation therapy (IMRT). It looks at which one leads to better swallowing function and overall quality of life. About 138 adults with HPV-related throat cancer are taking part. The goal i…
Matched conditions: OROPHARYNX CANCER
Phase: NA • Sponsor: Christian von Buchwald • Aim: Symptom relief
Last updated Jun 27, 2026 08:07 UTC
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Exercise and diet combo tested for head and neck cancer recovery
Symptom relief OngoingThis study tests whether a program combining resistance training and a Mediterranean diet is practical and helpful for people with head and neck cancer undergoing radiation. Forty participants will receive supervised exercise sessions and pre-made meals, plus dietary coaching. Th…
Matched conditions: OROPHARYNX CANCER
Phase: NA • Sponsor: H. Lee Moffitt Cancer Center and Research Institute • Aim: Symptom relief
Last updated Jun 27, 2026 08:01 UTC
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Throat cancer radiation trial targets saliva ducts to stop dry mouth
Symptom relief TerminatedThis study aimed to see if using MRI scans to guide radiation away from the main saliva ducts could reduce dry mouth in people with oropharynx cancer. The trial planned to compare standard radiation with a new approach that spares these ducts. However, the study was withdrawn bef…
Matched conditions: OROPHARYNX CANCER
Phase: NA • Sponsor: UNC Lineberger Comprehensive Cancer Center • Aim: Symptom relief
Last updated Jun 26, 2026 13:32 UTC
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Simple blood test may spot returning throat cancer sooner
Knowledge-focused OngoingThis study looks at whether a blood test that finds HPV DNA can spot throat cancer coming back after treatment, possibly earlier than usual scans. Researchers will follow 200 patients with HPV-positive oropharyngeal cancer to see how accurate the test is. The goal is to improve m…
Matched conditions: OROPHARYNX CANCER
Sponsor: Rigshospitalet, Denmark • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC