OROPHARYNX CANCER

This study tests a three-drug combination (carboplatin, nab-paclitaxel, and durvalumab) given before surgery to people with advanced head and neck cancer that can be removed. The goal is to shrink or eliminate the tumor so that radiation—which has harsh side effects—may not be ne…

This study tests whether the immunotherapy drug pembrolizumab (Keytruda) combined with radiation works better than standard chemotherapy (cisplatin) plus radiation for people with advanced head and neck cancer. About 126 participants with p16-positive cancer will be randomly assi…

This study was designed to see if using MRI scans to guide radiation therapy can better protect the salivary ducts and reduce dry mouth in people with oropharynx cancer. Dry mouth is a common and lasting side effect of radiation. The plan was to compare patient-reported dry mouth…

This study compares two treatments for early-stage throat cancer: robotic surgery or radiation therapy. It looks at which one leads to better quality of life, especially swallowing. About 138 people took part. The goal is to help patients and doctors choose the best option.

This study is testing whether a special diet and exercise program is practical and helpful for people who have had head and neck cancers (like mouth or throat cancer). The study will enroll 40 adults who are scheduled for radiation treatment. Researchers want to see if participan…

This study looks at whether a simple blood test that detects HPV DNA can find returning oropharynx cancer earlier than current methods like scans. Researchers will follow 200 patients who have finished treatment for HPV-positive oropharynx cancer. The goal is to see how accurate …