New program aims to speed up radiation for head and neck cancer patients

NCT ID NCT05793151

Recruiting now Disease control Sponsor: Medical University of South Carolina Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This trial tests a program called ENDURE that helps head and neck cancer patients start radiation therapy within 6 weeks after surgery. The program provides education, social support, and better coordination among doctors. Researchers will compare it to usual care in 532 adults with head and neck cancer to see if it improves timely treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Navigation-based multilevel intervention (ENDURE) including patient education, social support, care coordination, and referral tracking
What this could lead to: If successful, this program could help more head and neck cancer patients start their radiation therapy on time, potentially improving treatment outcomes.
What could go wrong: This is a behavioral intervention, not a drug or device, so its impact may be modest. Results depend on how well clinics adopt the program, and it may not work in all settings.

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Conditions

The condition(s) this trial relates to.

head and neck cancer Head and Neck Neoplasms head and neck squamous cell carcinoma hypopharynx squamous cell carcinoma laryngeal neoplasm laryngeal squamous cell carcinoma larynx cancer Mouth Neoplasms nasal cavity squamous cell carcinoma oral cavity cancer oral cavity squamous cell carcinoma oropharynx cancer oropharynx squamous cell carcinoma paranasal sinus squamous cell carcinoma Squamous Cell Carcinoma of Head and Neck

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEAD AND NECK CANCER HEAD AND NECK SQUAMOUS CELL CARCINOMA LARYNX CANCER ORAL CAVITY CANCER OROPHARYNX CANCER

Contacts and locations

Locations

Baylor College of Medicine
RECRUITING

Houston, Texas, 77030, United States
Duke University Medical Center
RECRUITING

Durham, North Carolina, 27710, United States
Medical University of South Carolina
RECRUITING

Charleston, South Carolina, 29425, United States
Washington University in St. Louis
RECRUITING

St Louis, Missouri, 63110, United States

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