OPIOID-RELATED DISORDERS
Clinical trials for OPIOID-RELATED DISORDERS explained in plain language.
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Brain-Zapping device tested as opioid withdrawal aid
Disease control CompletedThis study tested whether a medical device called the Bridge could help people with opioid addiction get through withdrawal. Researchers at Johns Hopkins enrolled 46 people with active addiction to stay in a research unit. They compared the real device against a fake device and a…
Matched conditions: OPIOID-RELATED DISORDERS
Phase: PHASE2, PHASE3 • Sponsor: Johns Hopkins University • Aim: Disease control
Last updated Mar 27, 2026 12:40 UTC
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Brain surgery trial offers hope for untreatable opioid addiction
Disease control CompletedThis study tested whether deep brain stimulation could help people with severe opioid addiction that hasn't responded to other treatments. Researchers implanted a device to deliver electrical pulses to specific brain areas involved in addiction and reward. They measured safety, o…
Matched conditions: OPIOID-RELATED DISORDERS
Phase: NA • Sponsor: West Virginia University • Aim: Disease control
Last updated Mar 23, 2026 15:14 UTC
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New program aims to stop addiction before it starts for At-Risk parents
Prevention CompletedThis study tested a new support program called PRE-FAIR, designed to prevent young parents involved with child welfare services from developing serious opioid or methamphetamine addictions. The program offered mental health support, parenting skills training, and help with other …
Matched conditions: OPIOID-RELATED DISORDERS
Phase: NA • Sponsor: Chestnut Health Systems • Aim: Prevention
Last updated Mar 30, 2026 14:32 UTC
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Hospital checklist aims to stop HIV spread in rural drug users
Prevention CompletedThis study tested a hospital checklist designed to help people who inject drugs get better care. It aimed to connect 60 rural patients with addiction treatment and HIV prevention medications like PrEP during their hospital stay. The goal was to see if this simple reminder system …
Matched conditions: OPIOID-RELATED DISORDERS
Phase: NA • Sponsor: University of Alabama at Birmingham • Aim: Prevention
Last updated Mar 30, 2026 14:27 UTC
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New nerve blocks could cut opioid use after breast surgery
Symptom relief CompletedThis study compared two different nerve block techniques to manage pain after breast reduction surgery. Researchers tested whether injections near the spine (erector spinae block) or near the shoulder blade (serratus anterior block) work better to reduce pain and limit opioid med…
Matched conditions: OPIOID-RELATED DISORDERS
Phase: NA • Sponsor: Sisli Hamidiye Etfal Training and Research Hospital • Aim: Symptom relief
Last updated Mar 30, 2026 14:34 UTC
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Art kits tested as a new tool to ease pain and improve mood
Symptom relief CompletedThis small, completed study explored whether people with chronic pain and opioid use disorder would use simple, self-guided art kits at home. Researchers gave 31 participants kits for activities like mandala painting and weaving to see if the practice could provide temporary reli…
Matched conditions: OPIOID-RELATED DISORDERS
Phase: NA • Sponsor: Montefiore Medical Center • Aim: Symptom relief
Last updated Mar 23, 2026 15:16 UTC
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New therapy aims to break link between pain and opioid relapse
Symptom relief CompletedThis study tested a counseling program called TOPPS for people with opioid addiction who are also dealing with chronic pain and depression. The program, delivered in a primary care doctor's office, taught patients skills to manage pain and mood without turning back to substance m…
Matched conditions: OPIOID-RELATED DISORDERS
Phase: NA • Sponsor: Boston University • Aim: Symptom relief
Last updated Mar 18, 2026 14:40 UTC
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Pregnant Moms' opioid treatment: which is better for Baby's brain?
Knowledge-focused CompletedThis study looked at whether two different medications for opioid addiction during pregnancy affect how babies' brains develop. Researchers compared a monthly injection to a daily dissolving tablet. They followed 71 infants to measure their thinking, language, and motor skills in…
Matched conditions: OPIOID-RELATED DISORDERS
Sponsor: T. John Winhusen, PhD • Aim: Knowledge-focused
Last updated Mar 24, 2026 12:01 UTC
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Scientists probe how addiction meds affect unborn babies
Knowledge-focused CompletedThis study aimed to understand how two different forms of buprenorphine, a medication for opioid addiction, work in pregnant women. Researchers compared a monthly injection to a daily dissolving tablet to see how drug levels in the mother's blood relate to the baby's health in th…
Matched conditions: OPIOID-RELATED DISORDERS
Sponsor: T. John Winhusen, PhD • Aim: Knowledge-focused
Last updated Mar 23, 2026 15:15 UTC
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Scientists scan brains to see how CBD fights opioid cravings
Knowledge-focused CompletedThis study used brain imaging to understand how CBD might help people with opioid addiction. Researchers scanned the brains of 66 people on methadone treatment after giving them either CBD or a placebo. The goal was to see how CBD affects brain activity and chemistry related to d…
Matched conditions: OPIOID-RELATED DISORDERS
Phase: PHASE2 • Sponsor: Yasmin Hurd • Aim: Knowledge-focused
Last updated Mar 20, 2026 14:48 UTC