OPIOID-RELATED DISORDERS

This study tested a 12-month program where nurses provided phone-based support to patients with depression and opioid use. 805 adults were randomly assigned to either receive the nurse support or continue with usual care. The goal was to see if this team-based approach could impr…

This study tested if deep brain stimulation (DBS) is safe and feasible for people with severe opioid addiction that hasn't improved with other treatments. One participant received either active or sham stimulation to brain areas linked to reward. The goal was to see if DBS could …

This study tested a simple checklist for hospital staff to help people who inject drugs get HIV prevention medicine (PrEP) and addiction treatment. Researchers worked with 60 HIV-negative adults with opioid use disorder at a hospital in Alabama. The goal was to see if this approa…

This study tested a program called PRE-FAIR to help prevent opioid and methamphetamine addiction in young parents (ages 16-30) already involved with child welfare services. The program combined mental health support, parenting help, and monitoring of drug use. Researchers compare…

This study looked at whether CBD (a cannabis compound) can lower craving and anxiety in people with opioid use disorder who are already on methadone. 66 adults received either CBD or a placebo, and brain scans were used to see how CBD affects brain activity. The goal was to under…

This study compared two types of nerve blocks (erector spinae plane block and serratus anterior plane block) for pain relief after breast reduction surgery. Eighty women received one of the two blocks before surgery, and researchers measured their pain scores and how much opioid …

This study tested a small device placed behind the ear that sends mild electrical pulses to help manage opioid withdrawal symptoms. 46 adults with opioid use disorder stayed in a research unit for 2-3 weeks. Some got the active device, some got a sham device, and some got standar…

This small study tested whether people with chronic pain and opioid problems would actually do art on their own at home, and if it helped their pain and mood. Thirty-one adults completed surveys before and after up to four art sessions. The results suggest that self-guided artmak…

This study tested a program called TOPPS for people taking buprenorphine for opioid use disorder who also have chronic pain. The program uses counseling and education to help patients manage pain without turning to opioids. Researchers compared it to a health education group in 1…

This study tested a mobile app called App for Independence-O (A4i-O) in 14 adults with opioid use disorder. Participants used the app for one month to see if it was easy to use and helpful. The goal was to gather feedback and check how the app works before larger studies.

This study looked at 97 pregnant women with opioid use disorder to understand how two forms of buprenorphine—a once-monthly shot and a daily tablet—affect both mother and baby. Researchers measured drug levels in the blood, fetal heart rate, and newborn withdrawal symptoms. The g…

This study followed 71 babies born to mothers who received one of two forms of buprenorphine for opioid use disorder during pregnancy. Researchers used the Bayley Scales of Infant Development to compare cognitive, language, and motor skills between the two groups. The goal was to…