NON-SMALL-CELL LUNG CARCINOMA

This study looked at how well the drug lorlatinib works for people with advanced non-small cell lung cancer that has a specific gene change (ALK). All 73 participants had already tried at least one other treatment and took lorlatinib pills at home. Researchers tracked how long th…

This phase 2 trial tested giving the immunotherapy drug pembrolizumab before and after surgery to 35 people with early-stage non-small cell lung cancer. The goal was to see if this approach is safe and helps the immune system attack cancer cells. The main focus was on whether pat…

This study tested a drug called capmatinib in 50 Indian adults with advanced non-small cell lung cancer that has a specific genetic change (MET exon 14 skipping mutation). The goal was to see how safe the drug is and how well it shrinks tumors. Participants took capmatinib pills,…

This study tested a new drug combination (vibostolimab plus pembrolizumab) against pembrolizumab alone in over 1,200 people with advanced PD-L1 positive non-small cell lung cancer. The goal was to see if the combination helps people live longer or keeps the cancer from growing lo…

This study tested a new immunotherapy drug, cemiplimab, against standard chemotherapy for people with advanced non-small cell lung cancer that has a specific marker (PD-L1). The goal was to see if cemiplimab helps patients live longer or keeps their cancer from growing longer tha…

This early-phase study tested a light-measuring system used during photodynamic therapy (PDT) for people with malignant mesothelioma, non-small cell lung cancer, or other chest cancers that have spread to the lining of the lungs. Nine participants received a light-activated drug …

This study looked at whether adding metformin (a common diabetes medicine) to standard chemotherapy and radiation helps people with stage III non-small cell lung cancer live longer without their cancer getting worse. About 170 adults with advanced lung cancer took part. The goal …

This early-phase study tested a treatment for people with advanced lung cancer that blocks their airways. Doctors injected a light-sensitive drug into the blood, then used a special laser to activate it inside the tumor, aiming to shrink it and relieve symptoms. The study include…

This study looked at whether a special type of scan called 4D PET-CT can help doctors plan radiation therapy better for people with non-small cell lung cancer. Seven patients had both a standard CT scan and a 4D PET-CT scan, and researchers compared the radiation target areas fro…

This study looked at whether a simple blood test can monitor lung cancer progression without needing to sample the tumor directly. Researchers checked for genetic changes in the blood of 200 lung cancer patients. The goal was to see if this non-invasive method could track how the…

This study looked at how doctors currently manage patients with a type of lung cancer that hasn't caused symptoms yet and is located in the center of the chest. Researchers followed 46 patients to see if they received radiation therapy right away or only later when symptoms appea…