NEUROFIBROMATOSIS 1
Clinical trials for NEUROFIBROMATOSIS 1 explained in plain language.
Never miss a new study
Get alerted when new NEUROFIBROMATOSIS 1 trials appear
Sign up with your email to follow new studies for NEUROFIBROMATOSIS 1, keep track of the ones that matter, and come back to a personal dashboard instead of checking manually.
By submitting, you agree to our Terms of use
-
Early trial tests pill to shrink painful NF1 tumors
Disease control OngoingThis early-stage study is testing the safety and effects of an oral medication called selumetinib in Chinese children and adults with neurofibromatosis type 1 (NF1) who have inoperable plexiform neurofibromas (tumors). Participants take the medication twice daily until their dise…
Matched conditions: NEUROFIBROMATOSIS 1
Phase: PHASE1 • Sponsor: AstraZeneca • Aim: Disease control
Last updated Apr 01, 2026 14:41 UTC
-
Kitchen spice & olive oil tested for rare genetic disorder
Disease control OngoingThis early-stage study is testing whether daily supplements of curcumin (from turmeric) and special high-phenolic olive oil are safe and might help control skin tumors in adults with neurofibromatosis type 1 (NF1). The 23 participants take the supplements twice daily for up to a …
Matched conditions: NEUROFIBROMATOSIS 1
Phase: PHASE1 • Sponsor: Masonic Cancer Center, University of Minnesota • Aim: Disease control
Last updated Mar 31, 2026 12:12 UTC
-
New hope for shrinking painful tumors in adults with rare genetic disorder
Disease control OngoingThis global study is testing whether the drug selumetinib can shrink painful, inoperable tumors in adults with Neurofibromatosis Type 1 (NF1). About 145 participants will be randomly assigned to receive either selumetinib or a placebo to see which is better at reducing tumor size…
Matched conditions: NEUROFIBROMATOSIS 1
Phase: PHASE3 • Sponsor: AstraZeneca • Aim: Disease control
Last updated Mar 31, 2026 12:12 UTC
-
New hope for kids with untreatable tumors
Disease control OngoingThis study tested an oral drug called selumetinib for children and young adults with neurofibromatosis type 1 (NF1) who have nerve tumors that cannot be removed by surgery. The main goals were to find a safe dose and see if the drug could shrink or stop these tumors from growing.…
Matched conditions: NEUROFIBROMATOSIS 1
Phase: PHASE1, PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Mar 30, 2026 14:29 UTC
-
Could a common cosmetic drug shrink painful skin tumors?
Disease control ENROLLING_BY_INVITATIONThis early-stage study is testing whether giving monthly injections of an FDA-approved drug called Kybella (deoxycholate) can safely reduce the size and improve the appearance of skin tumors in adults with Neurofibromatosis Type 1. Researchers will treat up to 50 tumors in a sing…
Matched conditions: NEUROFIBROMATOSIS 1
Phase: PHASE1 • Sponsor: Massachusetts General Hospital • Aim: Disease control
Last updated Mar 09, 2026 14:27 UTC
-
Hunting the clues: can scans predict deadly cancer in genetic disorder?
Knowledge-focused OngoingThis study aims to find better ways to predict which benign nerve tumors in people with Neurofibromatosis type 1 (NF1) might turn into a dangerous, hard-to-treat cancer called MPNST. Researchers will follow 80 participants considered at high risk, using annual whole-body MRI scan…
Matched conditions: NEUROFIBROMATOSIS 1
Sponsor: Johns Hopkins University • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:32 UTC
-
Mapping the mystery: 5-Year study tracks NF1 skin tumors with 3D cameras
Knowledge-focused OngoingThis study aims to understand how and why benign skin tumors grow in people with Neurofibromatosis Type 1 (NF1). Researchers at Johns Hopkins will follow 500 participants for five years, using annual 3D whole-body imaging to track changes in these tumors over time. The goal is to…
Matched conditions: NEUROFIBROMATOSIS 1
Sponsor: Johns Hopkins University • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:39 UTC
-
Blood test breakthrough could replace scans for NF1 tumor tracking
Knowledge-focused ENROLLING_BY_INVITATIONThis study aims to find signals in the blood that can tell doctors about tumor growth in people with Neurofibromatosis type 1 (NF1). Researchers will study 200 people with NF1, using blood tests and full-body MRI scans to see if specific blood markers match the size and number of…
Matched conditions: NEUROFIBROMATOSIS 1
Sponsor: Ann & Robert H Lurie Children's Hospital of Chicago • Aim: Knowledge-focused
Last updated Mar 23, 2026 15:14 UTC