NEUROFIBROMATOSIS 1
Clinical trials for NEUROFIBROMATOSIS 1 explained in plain language.
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New hope for NF1 patients: drug trial targets painful tumors
Disease control OngoingThis study tests a drug called selumetinib in adults with neurofibromatosis type 1 (NF1) who have painful, inoperable nerve tumors. The goal is to see if the drug can shrink these tumors and reduce pain. About 145 participants will receive either selumetinib or a placebo to measu…
Matched conditions: NEUROFIBROMATOSIS 1
Phase: PHASE3 • Sponsor: AstraZeneca • Aim: Disease control
Last updated May 14, 2026 12:05 UTC
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Promising drug may tame NF1 tumors without surgery
Disease control OngoingThis study tests an experimental drug, selumetinib, in children and young adults with neurofibromatosis type 1 (NF1) who have nerve tumors that cannot be removed by surgery. The goal is to see if the drug can shrink the tumors or stop them from growing. Participants take the drug…
Matched conditions: NEUROFIBROMATOSIS 1
Phase: PHASE1, PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 11, 2026 20:48 UTC
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New drug shows promise for rare nerve tumors in chinese patients
Disease control OngoingThis early-stage study tests a drug called selumetinib in 32 Chinese children and adults with neurofibromatosis type 1 (NF1) who have nerve tumors that cannot be surgically removed. The main goals are to check the drug's safety and how the body processes it, while also measuring …
Matched conditions: NEUROFIBROMATOSIS 1
Phase: PHASE1 • Sponsor: AstraZeneca • Aim: Disease control
Last updated May 08, 2026 12:02 UTC
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Fat-Dissolving drug may shrink NF1 skin bumps in repeat doses
Symptom relief ENROLLING_BY_INVITATIONThis study tests whether monthly injections of Kybella (a drug that dissolves fat) can safely shrink skin bumps called cutaneous neurofibromas in people with Neurofibromatosis Type 1. Fifteen adults will receive up to six treatments, each spaced at least 30 days apart. Researcher…
Matched conditions: NEUROFIBROMATOSIS 1
Phase: PHASE1 • Sponsor: Massachusetts General Hospital • Aim: Symptom relief
Last updated May 04, 2026 16:23 UTC
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Can olive oil and turmeric shrink NF1 tumors? new study tests safety
Symptom relief OngoingThis early-phase study tests whether taking curcumin (from turmeric) and a special olive oil rich in healthy compounds can safely help adults with NF1 who have skin tumors. About 23 participants take these supplements twice daily for up to 12 months. The main goal is to check for…
Matched conditions: NEUROFIBROMATOSIS 1
Phase: PHASE1 • Sponsor: Masonic Cancer Center, University of Minnesota • Aim: Symptom relief
Last updated May 01, 2026 15:57 UTC
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Blood test could spot hidden tumors in kids with NF1
Knowledge-focused ENROLLING_BY_INVITATIONThis study looks for signals in the blood that could show whether a person with Neurofibromatosis type 1 (NF1) has plexiform neurofibroma tumors. Currently, finding these tumors requires whole-body MRI scans. Researchers will collect blood samples and compare them with MRI result…
Matched conditions: NEUROFIBROMATOSIS 1
Sponsor: Ann & Robert H Lurie Children's Hospital of Chicago • Aim: Knowledge-focused
Last updated May 15, 2026 11:57 UTC
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500 NF1 patients join 5-Year skin tumor watch
Knowledge-focused OngoingThis study follows 500 people with neurofibromatosis type 1 (NF1) to track how their skin tumors (cutaneous neurofibromas) grow and change over five years. Researchers use a special 3D camera to measure tumors without touching the skin. The goal is to better understand these tumo…
Matched conditions: NEUROFIBROMATOSIS 1
Sponsor: Johns Hopkins University • Aim: Knowledge-focused
Last updated May 14, 2026 12:05 UTC
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New study aims to predict cancer risk in NF1 patients before it starts
Knowledge-focused OngoingThis study follows 80 people with neurofibromatosis type 1 (NF1) who are at high risk for developing malignant peripheral nerve sheath tumors (MPNST). Researchers will use yearly whole-body MRI scans, blood samples, and checkups to track changes in nerve tumors over time. The goa…
Matched conditions: NEUROFIBROMATOSIS 1
Sponsor: Johns Hopkins University • Aim: Knowledge-focused
Last updated May 14, 2026 12:03 UTC