New hope for NF1 patients: targeted drug shrinks inoperable tumors in early trial

NCT ID NCT04590235

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tests a drug called selumetinib in 32 Chinese children and adults with neurofibromatosis type 1 (NF1) who have nerve tumors that cannot be surgically removed. The goal is to check the drug's safety and how well it works at shrinking these tumors. Participants take the drug by mouth, and doctors monitor side effects and tumor size using MRI scans.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary โ€” we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

neurofibromatosis type 1 plexiform neurofibroma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Research Site

    Shanghai, 200011, China

  • Research Site

    Shanghai, CN-200092, China