NEUROFIBROMATOSIS 1
Clinical trials for NEUROFIBROMATOSIS 1 explained in plain language.
Never miss a new study
Get alerted when new NEUROFIBROMATOSIS 1 trials appear
Sign up with your email to follow new studies for NEUROFIBROMATOSIS 1, keep track of the ones that matter, and come back to a personal dashboard instead of checking manually.
By submitting, you agree to our Terms of use
-
Antioxidant drug shows promise for kids with NF1
Disease control CompletedThis study tested whether N-acetylcysteine (NAC), an antioxidant drug, can improve motor skills and learning in children with neurofibromatosis type 1 (NF1). Twenty-five children aged 8 to 16 took NAC or a placebo for 8 weeks. The goal was to see if NAC is safe and helps with mov…
Matched conditions: NEUROFIBROMATOSIS 1
Phase: PHASE2 • Sponsor: Children's Hospital Medical Center, Cincinnati • Aim: Disease control
Last updated Jun 27, 2026 13:02 UTC
-
New drug combo shows promise for rare nerve tumors
Disease control CompletedThis phase 2 trial tested two drugs, selumetinib and sirolimus, in 21 people with advanced malignant peripheral nerve sheath tumors (MPNST), a rare cancer often linked to neurofibromatosis type 1. The goal was to see if the combination could shrink or stabilize tumors. The study …
Matched conditions: NEUROFIBROMATOSIS 1
Phase: PHASE2 • Sponsor: Sarcoma Alliance for Research through Collaboration • Aim: Disease control
Last updated Jun 27, 2026 12:38 UTC
-
New gel could shrink neurofibroma tumors without surgery
Disease control CompletedThis phase 2 trial tested a gel called NFX-179 on skin tumors in 199 adults with neurofibromatosis type 1. Participants applied the gel daily for 26 weeks. The study measured safety and whether tumors shrank in size or height. Results suggest the gel may help reduce tumor volume,…
Matched conditions: NEUROFIBROMATOSIS 1
Phase: PHASE2 • Sponsor: NFlection Therapeutics, Inc. • Aim: Disease control
Last updated Jun 27, 2026 09:05 UTC
-
Could a common supplement help kids with NF1 learn and move better?
Symptom relief CompletedThis study tested whether N-acetylcysteine (NAC), an over-the-counter antioxidant, could improve learning and motor skills in children with neurofibromatosis type 1 (NF1). Five children aged 8 to 16 took NAC or a placebo to see if it helped with movement and attention problems. T…
Matched conditions: NEUROFIBROMATOSIS 1
Phase: PHASE2 • Sponsor: Children's Hospital Medical Center, Cincinnati • Aim: Symptom relief
Last updated Jun 27, 2026 12:23 UTC
-
Video-Based stress program aims to ease life with neurofibromatosis
Symptom relief CompletedThis study tested two stress and symptom management programs for adults with neurofibromatosis (NF1, NF2, or schwannomatosis). The programs were delivered through live videoconferencing over 8 weekly sessions. Researchers measured changes in quality of life and emotional well-bei…
Matched conditions: NEUROFIBROMATOSIS 1
Phase: NA • Sponsor: Massachusetts General Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 08:07 UTC
-
Chill out: skin cooling may ease pain of NF1 treatments
Symptom relief CompletedThis study tested whether cooling the skin before or during laser and injection treatments for neurofibromatosis type 1 (NF1) skin bumps can reduce pain. Thirteen adults with NF1 received four different treatments (two lasers and two injections) on both cooled and non-cooled skin…
Matched conditions: NEUROFIBROMATOSIS 1
Phase: PHASE1 • Sponsor: Massachusetts General Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 07:58 UTC
-
Scientists hunt for genes behind NF1 skin tumors
Knowledge-focused CompletedThis completed study at Stanford University looked at the DNA of over 1,000 adults with Neurofibromatosis Type 1 (NF1) to find genetic differences that might explain why some people develop more skin neurofibromas than others. Participants provided blood or saliva samples for gen…
Matched conditions: NEUROFIBROMATOSIS 1
Sponsor: Stanford University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC