NEUROFIBROMATOSIS 1
Clinical trials for NEUROFIBROMATOSIS 1 explained in plain language.
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New gel shows promise for shrinking painful skin tumors in rare genetic condition
Disease control CompletedThis study tested a gel called NFX-179 on skin tumors (cutaneous neurofibromas) in 199 adults with neurofibromatosis type 1. Participants applied the gel daily for 6 months to up to 10 tumors. The goal was to see if the gel safely shrinks the tumors. Results showed some tumors re…
Matched conditions: NEUROFIBROMATOSIS 1
Phase: PHASE2 • Sponsor: NFlection Therapeutics, Inc. • Aim: Disease control
Last updated May 17, 2026 02:06 UTC
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Video-Based resiliency training shows promise for neurofibromatosis patients
Symptom relief CompletedThis study tested two stress and symptom management programs delivered via live video for 228 adults with neurofibromatosis (NF1, NF2, or schwannomatosis). The goal was to see if these programs could improve physical and psychological quality of life. Participants had to have dif…
Matched conditions: NEUROFIBROMATOSIS 1
Phase: NA • Sponsor: Massachusetts General Hospital • Aim: Symptom relief
Last updated May 17, 2026 02:05 UTC
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Could a common supplement help kids with NF1 think and move better?
Symptom relief CompletedThis study tested whether N-acetylcysteine (NAC), an over-the-counter antioxidant, could improve learning, behavior, and motor skills in children aged 8-16 with neurofibromatosis type 1 (NF1). Only 5 children participated, and the main goal was to measure changes in motor functio…
Matched conditions: NEUROFIBROMATOSIS 1
Phase: PHASE2 • Sponsor: Children's Hospital Medical Center, Cincinnati • Aim: Symptom relief
Last updated May 13, 2026 16:03 UTC
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Chill out: cooling skin may ease pain of NF1 procedures
Symptom relief CompletedThis early-phase study tested whether cooling the skin before treatment can help people with Neurofibromatosis Type 1 (NF1) tolerate painful procedures for skin bumps. Thirteen adults received four different treatments (lasers, injections) on both cooled and non-cooled skin spots…
Matched conditions: NEUROFIBROMATOSIS 1
Phase: PHASE1 • Sponsor: Massachusetts General Hospital • Aim: Symptom relief
Last updated May 05, 2026 11:53 UTC
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Massive DNA hunt for clues behind NF1 skin tumors
Knowledge-focused CompletedThis study created a large genetic database from over 1,000 adults with neurofibromatosis type 1 (NF1) to find DNA differences that explain why skin tumors vary so much between patients. Researchers collected blood or saliva samples and medical information to look for genetic var…
Matched conditions: NEUROFIBROMATOSIS 1
Sponsor: Stanford University • Aim: Knowledge-focused
Last updated May 11, 2026 20:47 UTC