NEUROFIBROMATOSIS 1
Clinical trials for NEUROFIBROMATOSIS 1 explained in plain language.
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New gel shows promise in shrinking painful skin tumors
Disease control CompletedThis study tested whether a gel called NFX-179 could safely reduce the size of skin tumors in adults with neurofibromatosis type 1 (NF1). 199 participants applied the gel or a placebo to 10 specific tumors on their face, chest, or arms once daily for six months. Researchers measu…
Matched conditions: NEUROFIBROMATOSIS 1
Phase: PHASE2 • Sponsor: NFlection Therapeutics, Inc. • Aim: Disease control
Last updated Mar 27, 2026 12:40 UTC
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Virtual training helps NF patients cope with stress and symptoms
Symptom relief CompletedThis study tested two different online stress and symptom management programs for adults with neurofibromatosis (NF1, NF2, or Schwannomatosis). Researchers compared how these live video programs affected participants' quality of life, stress levels, and ability to cope with their…
Matched conditions: NEUROFIBROMATOSIS 1
Phase: NA • Sponsor: Massachusetts General Hospital • Aim: Symptom relief
Last updated Apr 01, 2026 14:41 UTC
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Cooling skin could ease pain of tumor treatments
Symptom relief CompletedThis study tested whether cooling the skin could make several non-invasive treatments for Neurofibromatosis Type 1 (NF1) skin tumors less painful. Thirteen adults with NF1 received treatments like lasers and injections on paired tumor sites, with one site cooled and the other not…
Matched conditions: NEUROFIBROMATOSIS 1
Phase: PHASE1 • Sponsor: Massachusetts General Hospital • Aim: Symptom relief
Last updated Mar 30, 2026 14:35 UTC
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Scientists hunt genetic clues to explain why NF1 varies so much
Knowledge-focused CompletedThis study aimed to understand why people with Neurofibromatosis Type 1 (NF1) have such different experiences with skin tumors. Researchers collected DNA and health information from over 1,000 adults with NF1 to look for common genetic patterns linked to tumor development. The go…
Matched conditions: NEUROFIBROMATOSIS 1
Sponsor: Stanford University • Aim: Knowledge-focused
Last updated Mar 31, 2026 12:11 UTC