New hope for NF1 patients: drug trial targets painful tumors
NCT ID NCT04924608
First seen Nov 01, 2025 · Last updated Apr 25, 2026 · Updated 31 times
Summary
This study tests a drug called selumetinib in adults with neurofibromatosis type 1 (NF1) who have painful nerve tumors that cannot be removed by surgery. The goal is to see if the drug can shrink these tumors and reduce pain. About 145 participants worldwide will receive either selumetinib or a placebo, and their tumor size and pain levels will be tracked over time.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Research Site
Gainesville, Florida, 32610, United States
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Research Site
Rockville, Maryland, 20852, United States
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St Louis, Missouri, 63156, United States
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Commack, New York, 11725, United States
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Melbourne, 3000, Australia
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St Leonards, 2065, Australia
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Porto Alegre, 90035-903, Brazil
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Ribeirão Preto, 14051-140, Brazil
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São Paulo, 045202-001, Brazil
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Toronto, Ontario, M5G 2C4, Canada
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Montreal, Quebec, H4A 3J1, Canada
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Beijing, 100070, China
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Beijing, 100730, China
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Guangzhou, 510060, China
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Shenyang, 110001, China
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Créteil, 94000, France
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Lyon, 69008, France
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Toulouse, 31059, France
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Hamburg, 20246, Germany
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Tübingen, 72076, Germany
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Würzburg, 97080, Germany
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Milan, 20133, Italy
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Naples, 80131, Italy
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Roma, 00165, Italy
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Research Site
Minatoku, 105-8471, Japan
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Nagoya, 466-8560, Japan
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Shinjuku-ku, 160-8582, Japan
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Bydgoszcz, 85-094, Poland
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Moscow, 115522, Russia
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Moscow, 125412, Russia
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Badalona, 08916, Spain
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Madrid, 28041, Spain
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London, SE1 9RT, United Kingdom
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Research Site
Manchester, M20 4BX, United Kingdom
Conditions
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