Could a Fat-Dissolving drug shrink NF1 skin tumors? new trial aims to find out

NCT ID NCT06300502

First seen Nov 20, 2025 · Last updated May 22, 2026 · Updated 23 times

Summary

This early-phase trial tests whether monthly injections of Kybella (a drug already approved for fat reduction) can safely shrink cutaneous neurofibromas—small, benign skin tumors—in people with Neurofibromatosis Type 1. Up to 15 adults will receive up to 6 monthly treatments, with researchers monitoring side effects, tumor size, and patient satisfaction. The goal is to see if repeat treatments can improve the appearance of these tumors without causing serious skin reactions.

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Contacts and locations

Locations

  • Wellman Center for Photomedicine

    Boston, Massachusetts, 02114, United States

Conditions

Explore the condition pages connected to this study.