MILD COGNITIVE IMPAIRMENT (MCI)
Clinical trials for MILD COGNITIVE IMPAIRMENT (MCI) explained in plain language.
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Brain-Boosting combo shows promise for seniors at risk of dementia
Disease control CompletedThis study tested a combined program of health education, cognitive training, and traditional Chinese exercises in 235 older adults with mild cognitive impairment. The goal was to see if this approach could help maintain or improve memory and thinking skills. Participants were ag…
Matched conditions: MILD COGNITIVE IMPAIRMENT (MCI)
Phase: NA • Sponsor: Xiaoying Wang • Aim: Disease control
Last updated Jun 27, 2026 12:33 UTC
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Can AI software sharpen Alzheimer's diagnosis?
Diagnosis CompletedThis study tested whether a computer program called SCALE PET helps doctors more accurately spot signs of Alzheimer's disease in brain scans. Researchers looked at 190 past scans from people with Alzheimer's or mild memory problems. Four doctors read the scans twice—once with the…
Matched conditions: MILD COGNITIVE IMPAIRMENT (MCI)
Phase: NA • Sponsor: NEUROPHET • Aim: Diagnosis
Last updated Jun 27, 2026 09:06 UTC
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Your voice may reveal Alzheimer's: new app tested for diagnosis
Diagnosis CompletedThis study tested a smartphone app that analyzes voice recordings to see if it can accurately diagnose mild cognitive impairment (MCI) and Alzheimer's disease. Researchers compared the app's diagnosis to a doctor's diagnosis in 150 adults aged 50 and older. The goal was to see if…
Matched conditions: MILD COGNITIVE IMPAIRMENT (MCI)
Phase: NA • Sponsor: Hackensack Meridian Health • Aim: Diagnosis
Last updated Jun 27, 2026 08:10 UTC
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Simple blood test could spot Alzheimer's early
Diagnosis CompletedThis study is working on a blood test to help diagnose Alzheimer's disease. Researchers are measuring two specific markers in the blood of 200 people—some with Alzheimer's and some healthy—to see if these markers can reliably tell the difference. The goal is to create a simple, n…
Matched conditions: MILD COGNITIVE IMPAIRMENT (MCI)
Sponsor: Amoneta Diagnostics SAS • Aim: Diagnosis
Last updated Jun 27, 2026 08:05 UTC
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Robot teachers take on dementia: 8-Week course shows promise
Prevention CompletedThis study tested whether an 8-week course led by a robot (Kebbi) could help prevent cognitive decline in 80 community-dwelling adults aged 65+ with mild cognitive impairment. The experimental group interacted with the robot in small groups, playing board games and learning, whil…
Matched conditions: MILD COGNITIVE IMPAIRMENT (MCI)
Phase: NA • Sponsor: National Taiwan Normal University • Aim: Prevention
Last updated Jun 27, 2026 12:08 UTC
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Could a Balloon-Popping game boost brain health in older adults?
Symptom relief CompletedThis study explores whether a mixed reality exergame—a video game that combines physical movement—can help older adults with mild cognitive impairment (MCI) improve their thinking skills and motivation to exercise. Participants play a balloon-popping game using special glasses th…
Matched conditions: MILD COGNITIVE IMPAIRMENT (MCI)
Phase: NA • Sponsor: Mahidol University • Aim: Symptom relief
Last updated Jun 27, 2026 14:01 UTC
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Robot caregiver? AI assistant tested for dementia patients at home
Symptom relief CompletedThis study tested a software system that uses a humanoid robot to give cognitive and motor tests to people with early Alzheimer's or other mild to moderate dementia. The goal was to see if the robot could effectively administer tests like the Mini Mental State Exam (MMSE) and hel…
Matched conditions: MILD COGNITIVE IMPAIRMENT (MCI)
Phase: NA • Sponsor: IRCCS Centro Neurolesi Bonino Pulejo • Aim: Symptom relief
Last updated Jun 27, 2026 12:29 UTC
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Robot buddy boosts brain and mood in dementia study
Symptom relief CompletedThis study tested whether a social robot named Kebbi could improve thinking, heart rate patterns, and emotional well-being in 136 older adults with mild dementia living in long-term care. Participants in the robot group spent 30 minutes with Kebbi three times a week for 12 weeks,…
Matched conditions: MILD COGNITIVE IMPAIRMENT (MCI)
Phase: NA • Sponsor: National Tainan Junior College of Nursing • Aim: Symptom relief
Last updated Jun 27, 2026 12:23 UTC
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Can virtual nostalgia boost brain health in seniors?
Symptom relief CompletedThis study tested whether a virtual reality program featuring nostalgic scenes from Taiwanese culture could improve mood, life satisfaction, and thinking skills in older adults with mild cognitive impairment or mild dementia. Sixty-four participants aged 65 and older were randoml…
Matched conditions: MILD COGNITIVE IMPAIRMENT (MCI)
Phase: NA • Sponsor: National Taiwan Normal University • Aim: Symptom relief
Last updated Jun 27, 2026 12:23 UTC
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VR hand games may sharpen aging brains
Symptom relief CompletedThis study tested whether doing hand exercises in a virtual reality (VR) environment could improve thinking skills and hand dexterity in older adults with mild cognitive impairment (MCI). 29 participants were split into two groups: one did VR-based hand activities (like virtual c…
Matched conditions: MILD COGNITIVE IMPAIRMENT (MCI)
Phase: NA • Sponsor: Istinye University • Aim: Symptom relief
Last updated Jun 27, 2026 12:06 UTC
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Could a graphene cap boost brain health in seniors?
Symptom relief CompletedThis completed study tested whether wearing a special graphene cap that emits far-infrared heat could improve thinking and mood in older adults with mild cognitive decline or Alzheimer's. 126 participants were split into groups based on their cognitive level and received either t…
Matched conditions: MILD COGNITIVE IMPAIRMENT (MCI)
Phase: NA • Sponsor: Institute of Psychology, Chinese Academy of Sciences • Aim: Symptom relief
Last updated Jun 27, 2026 12:00 UTC
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Sleep sounds may sharpen memory in early memory loss
Symptom relief CompletedThis study tested a device that plays soft sounds during deep sleep to help memory in people with amnestic mild cognitive impairment (aMCI), a condition that often leads to Alzheimer's. 37 participants received either real or silent (placebo) sounds while sleeping. Researchers me…
Matched conditions: MILD COGNITIVE IMPAIRMENT (MCI)
Phase: NA • Sponsor: Bitbrain • Aim: Symptom relief
Last updated Jun 27, 2026 09:05 UTC
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Dance your way to sharper thinking: new study tests creative movement for mild cognitive impairment
Symptom relief CompletedThis completed trial tested whether combining creative dance with a problem-solving strategy (CO-OP) could improve thinking skills like attention, memory, and multitasking in 26 older adults with mild cognitive impairment. Participants did either CO-OP alone or CO-OP plus dance f…
Matched conditions: MILD COGNITIVE IMPAIRMENT (MCI)
Phase: NA • Sponsor: Çankırı Karatekin University • Aim: Symptom relief
Last updated Jun 27, 2026 08:05 UTC
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Sabroxy™ shows promise for mild memory loss in small trial
Symptom relief CompletedThis study tested whether Sabroxy™, a supplement made from the bark of the Oroxylum indicum tree, can improve memory and thinking in adults aged 60 to 85 with mild cognitive concerns. About 70 participants took either Sabroxy™ or a placebo twice daily for 12 weeks. Researchers me…
Matched conditions: MILD COGNITIVE IMPAIRMENT (MCI)
Phase: NA • Sponsor: SF Research Institute, Inc. • Aim: Symptom relief
Last updated Jun 27, 2026 07:51 UTC
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Museum tours and art activities may lift spirits of those with mild dementia
Knowledge-focused CompletedThis study tested a 6-week museum-based programme called 'Refresh and Reconnect!' for older adults with mild cognitive impairment or mild dementia. Participants took guided tours and joined artist-led activities like dance, art, or drama. Researchers measured changes in quality o…
Matched conditions: MILD COGNITIVE IMPAIRMENT (MCI)
Phase: NA • Sponsor: Duke-NUS Graduate Medical School • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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New digital tool spots hidden Alzheimer's risk in routine doctor visits
Knowledge-focused CompletedThis study tested whether a digital tool that scans electronic health records could help find older adults (65+) who might have undetected mild cognitive impairment or Alzheimer's disease. Over 3,400 patients from primary care clinics were identified as high-risk by the tool. Res…
Matched conditions: MILD COGNITIVE IMPAIRMENT (MCI)
Phase: NA • Sponsor: Indiana University • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:01 UTC
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Music lessons for memory: pilot study tests feasibility
Knowledge-focused CompletedThis pilot study looked at whether older adults with mild cognitive impairment (MCI) find music training programs acceptable and enjoyable. Nineteen participants took part in 12 weeks of piano or music lessons, with home practice and mood tracking. The goal was to see if people w…
Matched conditions: MILD COGNITIVE IMPAIRMENT (MCI)
Phase: NA • Sponsor: University of Rochester • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:05 UTC
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Massive Alzheimer's study aims to sharpen diagnosis and trial design
Knowledge-focused CompletedThis completed observational study enrolled 1,141 participants with mild cognitive impairment or Alzheimer's disease. Researchers tracked changes in memory tests, brain scans, and other biomarkers over time. The goal was to improve how future clinical trials measure the disease, …
Matched conditions: MILD COGNITIVE IMPAIRMENT (MCI)
Sponsor: University of Southern California • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:01 UTC
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VR boosts brain health knowledge in seniors with early memory loss
Knowledge-focused CompletedThis study tested whether a virtual reality (VR) program could help older adults with mild cognitive impairment learn more about dementia and improve their health skills. 139 participants aged 65 and older were split into two groups: one used a VR health education module, and the…
Matched conditions: MILD COGNITIVE IMPAIRMENT (MCI)
Phase: NA • Sponsor: National Taiwan Normal University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:06 UTC