MAJOR DEPRESSION
Clinical trials for MAJOR DEPRESSION explained in plain language.
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Brain pulse therapy shows promise for treating depression
Disease control CompletedThis study tested whether a new, non-invasive brain stimulation therapy called Transcranial Pulse Stimulation (TPS) can help reduce symptoms of major depression. Researchers enrolled 80 adults with depression and randomly assigned them to receive either the real TPS treatment or …
Matched conditions: MAJOR DEPRESSION
Phase: NA • Sponsor: The Hong Kong Polytechnic University • Aim: Disease control
Last updated Mar 30, 2026 14:33 UTC
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Two-Week brain zap trial tests faster depression relief
Disease control CompletedThis study tested if a shorter, two-week course of magnetic brain stimulation could help adults with major depression. Researchers compared two different stimulation techniques to see which was better at reducing symptoms of depression and anxiety. 108 participants were randomly …
Matched conditions: MAJOR DEPRESSION
Phase: NA • Sponsor: Krajská zdravotní, a.s. - Nemocnice Most, o.z. • Aim: Disease control
Last updated Mar 25, 2026 14:08 UTC
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Sleeping your way to better mental health? brain zaps show promise
Disease control CompletedThis small Stanford study tested whether using magnetic pulses to gently stimulate the brain during sleep could help treat depression. It involved 15 people with moderate-to-severe depression who hadn't responded well to at least one antidepressant medication. Researchers measure…
Matched conditions: MAJOR DEPRESSION
Phase: NA • Sponsor: Stanford University • Aim: Disease control
Last updated Mar 23, 2026 15:15 UTC
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Patients call in, doctors listen: can phone messages improve mental health care?
Knowledge-focused CompletedThis small pilot study tested a new phone system called 'My Coach Connect' to see if it could help communication between patients and their mental health providers. Patients with conditions like depression or schizophrenia called in twice a week for four months to leave voice mes…
Matched conditions: MAJOR DEPRESSION
Phase: NA • Sponsor: RAND • Aim: Knowledge-focused
Last updated Mar 31, 2026 12:11 UTC
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Brain waves could reveal if depression meds will work
Knowledge-focused CompletedThis study tested whether brain wave scans could predict if people with depression would respond to antidepressant medication. Researchers monitored 38 patients with major depression using EEG brain scans while they received either medication or placebo. The goal was to see if ea…
Matched conditions: MAJOR DEPRESSION
Phase: PHASE4 • Sponsor: University of California, Los Angeles • Aim: Knowledge-focused
Last updated Mar 11, 2026 14:53 UTC