MAJOR DEPRESSION
Clinical trials for MAJOR DEPRESSION explained in plain language.
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Magic mushroom compound could lift Veterans' depression
Symptom relief Not yet recruitingThis study tests whether psilocybin, the active ingredient in magic mushrooms, can help veterans with depression that hasn't improved with standard treatments. About 240 veterans will receive either psilocybin or a placebo in a controlled setting. The goal is to see if it reduces…
Matched conditions: MAJOR DEPRESSION
Phase: PHASE3 • Sponsor: VA Office of Research and Development • Aim: Symptom relief
Last updated May 15, 2026 12:07 UTC
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LSD shortcut? new study tests quicker trip for depression relief
Symptom relief Not yet recruitingThis early-stage study tests if a shortened LSD experience, combined with the drug risperidone, can safely ease symptoms of major depression. Ten adults with moderate to severe depression will receive LSD followed by risperidone 45 minutes later. Researchers will monitor safety a…
Matched conditions: MAJOR DEPRESSION
Phase: PHASE1 • Sponsor: Johns Hopkins University • Aim: Symptom relief
Last updated May 15, 2026 11:55 UTC
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Could a psychedelic inhaler lift depression in hours?
Symptom relief Not yet recruitingThis study tests whether inhaling DMT, a fast-acting psychedelic, can quickly reduce depression and suicidal thoughts in adults with major depressive disorder. 140 participants will receive either a high or low dose, and those not improving after one week can get an extra high do…
Matched conditions: MAJOR DEPRESSION
Phase: PHASE2 • Sponsor: Universidade Federal do Rio Grande do Norte • Aim: Symptom relief
Last updated May 11, 2026 20:51 UTC
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Can a magic mushroom trip under anesthesia cure depression?
Symptom relief Not yet recruitingThis study tests whether giving psilocybin (the active ingredient in magic mushrooms) to people under general anesthesia can safely reduce symptoms of major depression. By using anesthesia, participants won't know if they got the drug or a placebo, making the study more reliable.…
Matched conditions: MAJOR DEPRESSION
Phase: PHASE2 • Sponsor: Stanford University • Aim: Symptom relief
Last updated May 06, 2026 16:15 UTC