MAJOR DEPRESSION
Clinical trials for MAJOR DEPRESSION explained in plain language.
Never miss a new study
Get alerted when new MAJOR DEPRESSION trials appear
Sign up with your email to follow new studies for MAJOR DEPRESSION, keep track of the ones that matter, and come back to a personal dashboard instead of checking manually.
By submitting, you agree to our Terms of use
-
Magic mushroom compound could lift Veterans' depression
Symptom relief Not yet recruitingThis study tests whether psilocybin, the active ingredient in magic mushrooms, can help veterans with depression that hasn't improved with at least two other treatments. 240 veterans will receive either psilocybin or a placebo in a controlled setting. The goal is to see if it red…
Matched conditions: MAJOR DEPRESSION
Phase: PHASE3 • Sponsor: VA Office of Research and Development • Aim: Symptom relief
Last updated Jun 27, 2026 13:03 UTC
-
Can anesthesia hide the trip? new study tests psilocybin for depression without the psychedelic experience
Symptom relief Not yet recruitingThis study tests whether giving psilocybin—a psychedelic drug being studied for depression—under general anesthesia can hide its mind-altering effects. That would allow researchers to run a truly blinded trial where neither patients nor doctors know who got the real drug. Ten adu…
Matched conditions: MAJOR DEPRESSION
Phase: PHASE2 • Sponsor: Stanford University • Aim: Symptom relief
Last updated Jun 27, 2026 12:29 UTC
-
Quick trip? LSD plus risperidone tested for depression
Symptom relief Not yet recruitingThis early-phase study tests whether a shortened LSD experience, combined with the drug risperidone, can safely ease symptoms of major depression. Ten adults with moderate to severe depression will receive LSD followed by risperidone 45 minutes later. Researchers will monitor saf…
Matched conditions: MAJOR DEPRESSION
Phase: PHASE1 • Sponsor: Johns Hopkins University • Aim: Symptom relief
Last updated Jun 27, 2026 12:03 UTC
-
Brain stimulation study seeks blood clues to depression treatment success
Knowledge-focused Not yet recruitingThis study looks at how a non-invasive brain stimulation technique called intermittent theta burst stimulation (iTBS) affects symptoms and blood markers in people with treatment-resistant depression. Fifty patients will receive iTBS sessions over four weeks, while fifty healthy v…
Matched conditions: MAJOR DEPRESSION
Phase: NA • Sponsor: Gulhane Training and Research Hospital • Aim: Knowledge-focused
Last updated Jul 01, 2026 00:00 UTC
-
Blood test clues for mental health disorders?
Knowledge-focused Not yet recruitingThis study will examine whether certain RNA molecules in the blood are different in people with psychiatric disorders like schizophrenia, depression, bipolar disorder, OCD, and panic disorder. Researchers will compare these molecules in patients who are not currently on medicatio…
Matched conditions: MAJOR DEPRESSION
Sponsor: Carmen Concerto • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:02 UTC
-
Scientists probe Brain's wiring to supercharge depression therapy
Knowledge-focused Not yet recruitingThis study aims to understand how a quick, non-invasive brain stimulation treatment called iTBS works in people with depression. Researchers will measure brain activity before and after stimulation in 100 participants (healthy volunteers and those with depression) using EEG and M…
Matched conditions: MAJOR DEPRESSION
Phase: PHASE1, PHASE2 • Sponsor: Mclean Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:35 UTC