Brain stimulation study seeks blood clues to depression treatment success
NCT ID NCT07673913
First seen Jun 29, 2026 · Last updated Jun 30, 2026 · Updated 1 time
Summary
This study looks at how a non-invasive brain stimulation technique called intermittent theta burst stimulation (iTBS) affects symptoms and blood markers in people with treatment-resistant depression. Fifty patients will receive iTBS sessions over four weeks, while fifty healthy volunteers provide baseline comparisons. Researchers will measure changes in depression severity and analyze blood samples for inflammatory and brain-health markers to better understand why some people respond to this treatment.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Intermittent theta burst stimulation (iTBS) via transcranial magnetic stimulation device
What this could lead to
If successful, this could identify blood markers that predict who will benefit from TMS, paving the way for personalized depression treatment.
What could go wrong
This is a small, early-stage study focused on understanding mechanisms, not proving a new treatment. Results may not apply to all patients with depression.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Gulhane Training and Research Hospital
Ankara, Ankara, 06000, Turkey (Türkiye)
Contact Phone: •••-•••-•••• Email: •••••@•••••