MAJOR DEPRESSION
Clinical trials for MAJOR DEPRESSION explained in plain language.
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New program aims to tackle diabetes in people with mental illness – but study never started
Disease control TerminatedThis study was designed to test whether a program called Lifestyle MIND can help people with serious mental illness (like schizophrenia or bipolar disorder) prevent or manage type 2 diabetes. The program includes group exercise and health classes twice a week for 10 weeks. Howeve…
Matched conditions: MAJOR DEPRESSION
Phase: NA • Sponsor: The University of Texas Health Science Center at San Antonio • Aim: Disease control
Last updated Jun 27, 2026 11:00 UTC
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New behavioral program aims to keep people with mental illness out of jail
Disease control OngoingThis study tests a new group program called Forging New Paths for adults with serious mental illness who have also been involved with the criminal justice system. The program combines cognitive behavioral therapy with social learning techniques to reduce aggression and help peopl…
Matched conditions: MAJOR DEPRESSION
Phase: NA • Sponsor: University of North Carolina, Chapel Hill • Aim: Disease control
Last updated Jun 27, 2026 07:51 UTC
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Can a One-Size-Fits-All therapy help depression and anxiety?
Symptom relief TerminatedThis study was designed to test whether a group therapy that uses basic communication skills common to all therapies can help people with depression, anxiety, PTSD, and stress. The therapy avoids specific methods like cognitive-behavioral therapy. The trial was withdrawn before a…
Matched conditions: MAJOR DEPRESSION
Phase: NA • Sponsor: University of Alabama at Birmingham • Aim: Symptom relief
Last updated Jun 27, 2026 14:00 UTC
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Zapping the brain to beat depression: a new hope?
Symptom relief OngoingThis study tests a new type of brain stimulation for people with treatment-resistant depression. Ten participants will receive both real and sham stimulation in a random order, with a break in between. The goal is to see if this personalized, closed-loop approach can safely impro…
Matched conditions: MAJOR DEPRESSION
Phase: NA • Sponsor: Ruijin Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 07:51 UTC
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ECT anesthesia showdown: does ketamine outperform propofol for severe depression?
Knowledge-focused OngoingThis study observes 65 adults with major depression or bipolar depression who are receiving electroconvulsive therapy (ECT) as part of their routine care. Researchers track how two different anesthetics—ketamine plus propofol versus propofol alone—affect depression severity, suic…
Matched conditions: MAJOR DEPRESSION
Sponsor: Nurdan Sağbaş • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:00 UTC
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Withdrawn depression study sought to measure food cravings with a computer test
Knowledge-focused TerminatedThis study was designed to test a new computer-based tool that uses pictures of food to measure how much pleasure and motivation people with major depression feel. The goal was to compare these responses between depressed patients and healthy volunteers to better understand depre…
Matched conditions: MAJOR DEPRESSION
Phase: NA • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:07 UTC