MAJOR DEPRESSION
Clinical trials for MAJOR DEPRESSION explained in plain language.
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Brain zaps tested as last hope for untreatable depression
Disease control OngoingThis study is testing a personalized brain stimulation treatment for people with severe depression that hasn't improved with standard medications. Ten participants with special research electrodes already implanted in their brains will receive both real and fake stimulation in ra…
Matched conditions: MAJOR DEPRESSION
Phase: NA • Sponsor: Ruijin Hospital • Aim: Disease control
Last updated Mar 20, 2026 14:48 UTC
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Study withdrawn before start: could lifestyle program help vulnerable group manage diabetes?
Disease control TerminatedThis study aimed to test whether a 10-week lifestyle program called Lifestyle MIND could help people with serious mental illness (like schizophrenia or bipolar disorder) better manage their type 2 diabetes. Researchers planned to compare a group that started the program immediate…
Matched conditions: MAJOR DEPRESSION
Phase: NA • Sponsor: The University of Texas Health Science Center at San Antonio • Aim: Disease control
Last updated Mar 18, 2026 14:42 UTC
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One therapy for all? study tests general approach to ease depression and anxiety
Symptom relief TerminatedThis study aimed to test if a general form of talk therapy, using common communication skills, could help adults with various mental health concerns like depression and anxiety. It planned to compare this approach to more specific, specialized therapies. The trial was withdrawn b…
Matched conditions: MAJOR DEPRESSION
Phase: NA • Sponsor: University of Alabama at Birmingham • Aim: Symptom relief
Last updated Mar 23, 2026 15:19 UTC
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Can food pictures unlock the secrets of depression?
Knowledge-focused TerminatedThis study aimed to test a new computer tool designed to measure two key problems in depression: reduced pleasure (liking) and low motivation (wanting). Researchers planned to have people with depression and healthy volunteers look at and compare colorful versus black-and-white p…
Matched conditions: MAJOR DEPRESSION
Phase: NA • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Mar 31, 2026 12:12 UTC
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Doctors watch how different anesthetics change ECT results
Knowledge-focused OngoingThis study observes how two different anesthesia options (ketamine+propofol vs propofol alone) affect people receiving electroconvulsive therapy (ECT) for severe depression or bipolar depression. Researchers will track 65 patients' depression levels, suicidal thoughts, and potent…
Matched conditions: MAJOR DEPRESSION
Sponsor: Nurdan Sağbaş • Aim: Knowledge-focused
Last updated Mar 24, 2026 12:03 UTC