ECT anesthesia showdown: does ketamine outperform propofol for severe depression?
NCT ID NCT07463911
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study observes 65 adults with major depression or bipolar depression who are receiving electroconvulsive therapy (ECT) as part of their routine care. Researchers track how two different anesthetics—ketamine plus propofol versus propofol alone—affect depression severity, suicidal thoughts, and dissociative symptoms over the course of ECT. The goal is to see if ketamine offers faster mood improvement without causing troubling side effects.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
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Locations
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Pamukkale University
Denizli, 20570, Turkey (Türkiye)