Zapping the brain to beat depression: a new hope?
NCT ID NCT07184697
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study tests a new type of brain stimulation for people with treatment-resistant depression. Ten participants will receive both real and sham stimulation in a random order, with a break in between. The goal is to see if this personalized, closed-loop approach can safely improve depressive symptoms.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
High-definition closed-loop transcranial alternating current stimulation (HD-ctACS) device
What this could lead to
If it works, this could point toward a new, non-invasive treatment option for people with depression that hasn't responded to standard medications.
What could go wrong
This is a very early, small trial with only 10 people. The results may not apply to everyone, and the treatment might not work better than a placebo.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Ruijin Hospital
Shanghai, Shanghai Municipality, 200025, China