Quick trip? LSD plus risperidone tested for depression

NCT ID NCT07503002

First seen Jun 27, 2026 · Last updated Jul 24, 2026 · Updated 3 times

Summary

This early-phase study tests whether a shortened LSD experience, combined with the drug risperidone, can safely ease symptoms of major depression. Ten adults with moderate to severe depression will receive LSD followed by risperidone 45 minutes later. Researchers will monitor safety and measure changes in depression scores over time.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

Locations

  • Johns Hopkins Center for Psychedelic and Consciousness Research

    Baltimore, Maryland, 21224, United States

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