Brain zaps battle blues: which TMS works best?

NCT ID NCT07181226

Completed Symptom relief Sponsor: Krajská zdravotní, a.s. - Nemocnice Most, o.z. Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tested two forms of transcranial magnetic stimulation (TMS) in 108 adults with major depression. Participants received either high-frequency or theta-burst TMS over two weeks. Researchers measured depression and anxiety before, after, and six weeks later to see which method worked better.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

repetitive transcranial magnetic stimulation (rTMS) device

What this could lead to

If successful, this could help doctors choose the best TMS method for treating depression and anxiety.

What could go wrong

This is a small, completed trial with only 108 participants. Results may not apply to everyone, and TMS can cause scalp discomfort or headache.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

anxiety disorder Depression major depressive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MAJOR DEPRESSION

Contacts and locations

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Locations

Krajská zdravotní, a.s. - Nemocnice Most, o.z.

Most, Ústí nad Labem Region, 434 64, Czechia