LUNG CANCERS

This study tests a new drug called AVZO-1418 in people with advanced solid tumors that have spread. The goal is to find a safe dose and see if it shrinks tumors. About 480 adults will take part, receiving the drug alone or with other treatments.

This study tests a new drug, KESONOTIDE™, in people with advanced solid tumors like prostate, breast, lung, ovarian, brain, pancreas, or skin cancer. The trial has two phases: first, finding the safest dose, then testing that dose in a larger group. About 80 participants will be …

This early-phase trial tests a new cell therapy called Super1 TCR-T in 15 people with advanced solid tumors (sarcoma, lung cancer, or melanoma) that have not responded to first-line treatment. The therapy involves taking a patient's own immune cells, genetically modifying them to…

This study is testing a new blood test to find early-stage lung cancer in heavy smokers who have no symptoms. Researchers will collect blood samples from 350 current or former smokers aged 30-80, including those with and without lung cancer. The goal is to see if the test can det…

This study tests a new robotic technology (ssRAB) to take tissue samples from lung nodules. Current methods work only about 70% of the time; the robot aims to be more accurate and safer. About 100 adults with lung nodules will undergo the procedure under anesthesia and be followe…

This study compares two types of nerve blocks for pain relief after lung cancer surgery. One block is done before surgery near the spine, the other during surgery between the ribs. Researchers will measure pain scores and how much additional pain medication patients need. The goa…

This study tests a special program designed to help people living in rural areas who have had lung cancer. The program focuses on improving quality of life, reducing stigma, and helping survivors stay engaged with their healthcare. About 300 participants will be randomly assigned…

This study compares standard palliative radiation for lung tumors with a newer, more focused technique that delivers a higher dose while sparing the esophagus. The goal is to improve or maintain quality of life by better controlling symptoms and reducing side effects. About 141 a…

This study tests whether a traditional Chinese medicine formula called modified Bufei Decoction can reduce cough, fatigue, and shortness of breath in elderly patients who have had lung cancer surgery. About 174 participants will receive either the herbal granules or a placebo twi…

This study is testing a supervised exercise program for people with cancer. Participants will take part in group exercise classes twice a week for 8 to 12 weeks. The goal is to see if the program helps improve physical activity levels and manage cancer-related symptoms. The study…

This trial compares conscious sedation versus general anesthesia for a lung biopsy procedure called pEBUS, used to diagnose lung nodules. About 306 adults with peripheral lung lesions will be randomly assigned to one of the two sedation methods. The goal is to see which approach …