New drug AVZO-1418 enters human trials for Hard-to-Treat cancers

NCT ID NCT07038343

Recruiting now Disease control Sponsor: Avenzo Therapeutics, Inc. Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a new drug called AVZO-1418 in people with advanced solid tumors that have spread. The goal is to find a safe dose and see if it shrinks tumors. About 480 adults will take part, receiving the drug alone or with other treatments.

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Conditions

The condition(s) this trial relates to.

biliary tract cancer Biliary Tract Neoplasms cancer carcinoma epithelial neoplasm lung cancer lung neoplasm malignant tumor of nasopharynx metastatic malignant neoplasm nasopharyngeal neoplasm Neoplasm Metastasis small cell lung carcinoma urothelial carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BILIARY TRACT CANCER (BTC) EPITHELIAL TUMOR LOCALLY ADVANCED LUNG CANCERS METASTATIC SOLID TUMORS NASOPHARYNGEAL CANCERS SOLID TUMOR CANCER UROTHELIAL CANCER

Contacts and locations

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Study contacts

Contact

Email: •••••@•••••

Locations

Avenzo Therapeutics Recruiting Site
RECRUITING

Atlanta, Georgia, 30322, United States
Avenzo Therapeutics Recruiting Site
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Boston, Massachusetts, 02215, United States
Avenzo Therapeutics Recruiting Site
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New York, New York, 10029, United States
Avenzo Therapeutics Recruiting Site
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Philadelphia, Pennsylvania, 19107, United States
Avenzo Therapeutics Recruiting Site
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Dallas, Texas, 75039, United States
Avenzo Therapeutics Recruiting Site
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Houston, Texas, 77054, United States
Avenzo Therapeutics Recruiting Site
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San Antonio, Texas, 78229, United States
Avenzo Therapeutics Recruiting Site
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West Valley City, Utah, 84119, United States
Avenzo Therapeutics Recruiting Site
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Fairfax, Virginia, 22031, United States
Avenzo Therapeutics Recruiting Site
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Seattle, Washington, 98109, United States
Avenzo Therapeutics Recruiting Site
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Gilbert, Arizona, 85234, United States
Avenzo Therapeutics Recruiting Site
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Los Angeles, California, 90048, United States
Avenzo Therapeutics Recruiting Site
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Denver, Colorado, 80218, United States
Avenzo Therapeutics Recruiting Site
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New Haven, Connecticut, 06510, United States
Avenzo Therapeutics Recruiting Site
RECRUITING

Washington D.C., District of Columbia, 20007, United States
Avenzo Therapeutics Recruiting Site
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Orlando, Florida, 32827, United States
Avenzo Therapeutics Recruiting Site
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Sarasota, Florida, 34232, United States
Avenzo Therapeutics Recruiting Site
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Tampa, Florida, 33612, United States

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