LUNG CANCERS

This study tests a new drug, KESONOTIDE™, in people with advanced solid tumors like prostate, breast, lung, ovarian, pancreatic, skin cancer, or glioblastoma. The main goal is to check if the drug is safe and tolerable, and to find the right dose. About 80 adults will take part i…

This early-phase trial tests a new treatment for people with advanced solid tumors (sarcoma, lung cancer, or melanoma) that have not responded to first-line therapy. The treatment involves taking a patient's own immune cells, modifying them in the lab to better recognize and atta…

This study tests a new drug called AVZO-1418 in people with advanced solid tumors that have spread. The goal is to find a safe dose and see if it shrinks tumors. About 430 adults will take part. The drug is given through a vein, alone or with other treatments.

This study aims to develop a blood test that can detect early-stage lung cancer in heavy smokers who have no symptoms. Researchers will collect blood samples from 350 current or former smokers, including those with and without lung cancer, and track their health for two years. Th…

This study tests a new robotic technology (ssRAB) to take tissue samples from lung nodules. Current methods work only about 70% of the time, sometimes requiring riskier procedures. The robot uses sensors to guide a thin tube more accurately to the nodule. 100 adults with lung nod…

This study tests a special program designed to improve quality of life for people living in rural areas who have had lung cancer. The program includes support to reduce stigma and help survivors stay active in their own care. About 300 participants will be randomly assigned to ei…

This study looks at whether a traditional Chinese herbal medicine, called modified Bufei decoction, can reduce common symptoms like cough, tiredness, and shortness of breath in people aged 65 and older who have had lung cancer surgery. About 174 participants will receive either t…

This study compares standard palliative radiation for lung tumors with a newer technique that delivers a higher dose while sparing the esophagus. The goal is to improve or maintain quality of life by reducing side effects and prolonging survival. About 141 adults with lung cancer…

This study tests an 8 to 12-week exercise program for people with or past cancer. The program includes supervised exercise classes, either online or in person. The goal is to help participants become more active and reduce cancer-related symptoms like fatigue. About 740 adults ac…

This study compares two types of nerve blocks—erector spinae and intercostal—for controlling pain after lung surgery. About 120 adults having video-assisted lung procedures will receive one of the two blocks. Researchers will measure pain scores and pain medication use for up to …

This study compares two sedation methods—general anesthesia (fully asleep) and conscious sedation (awake but relaxed)—for a lung biopsy procedure called radial endobronchial ultrasound. About 306 adults with small lung nodules will take part to see which method helps doctors get …