LOCALLY ADVANCED SOLID TUMOR
Clinical trials for LOCALLY ADVANCED SOLID TUMOR explained in plain language.
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Radioactive nanoparticles target Tough-to-Treat cancers in new trial
Disease control Recruiting nowThis is a first-in-human study testing a new experimental drug called 177Lu-SN201 in adults with advanced solid tumors that have progressed despite standard treatments. The drug is a radioactive nanoparticle designed to accumulate in tumors. The main goals are to find a safe and …
Matched conditions: LOCALLY ADVANCED SOLID TUMOR
Phase: PHASE1, PHASE2 • Sponsor: Spago Nanomedical AB • Aim: Disease control
Last updated Mar 31, 2026 12:12 UTC
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New hope for Tough-to-Treat lung cancer: first patients test novel drug
Disease control Recruiting nowThis is the first study in people testing a new oral drug called NVL-330 for advanced lung cancer that has a specific genetic change called HER2. The main goals are to find a safe dose and see how the body processes the drug. Researchers will also look for early signs that the dr…
Matched conditions: LOCALLY ADVANCED SOLID TUMOR
Phase: PHASE1 • Sponsor: Nuvalent Inc. • Aim: Disease control
Last updated Mar 31, 2026 12:11 UTC
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New hope drug targets Tough-to-Treat advanced cancers
Disease control Recruiting nowThis study is testing a new oral medication called NVL-655 for people with advanced cancers that have a specific genetic change called ALK. The trial aims to find the safest and most effective dose and see how well the drug shrinks tumors. It's for adults with advanced lung cance…
Matched conditions: LOCALLY ADVANCED SOLID TUMOR
Phase: PHASE1, PHASE2 • Sponsor: Nuvalent Inc. • Aim: Disease control
Last updated Mar 27, 2026 12:40 UTC
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New cancer drug targets genetic weakness in advanced tumors
Disease control Recruiting nowThis early-stage trial is testing a new drug called FOG-001 for people with advanced or spreading cancers that have specific genetic mutations. Researchers want to find the safest dose and see if the drug can shrink tumors or slow cancer growth. The study will include 575 partici…
Matched conditions: LOCALLY ADVANCED SOLID TUMOR
Phase: PHASE1, PHASE2 • Sponsor: Parabilis Medicines, Inc. • Aim: Disease control
Last updated Mar 27, 2026 12:39 UTC
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New hope for advanced cancer patients in early drug trial
Disease control Recruiting nowThis early-stage study is testing a new drug called IPN60300 in adults with advanced solid tumors that have spread or cannot be removed by surgery. The main goals are to find a safe and effective dose and to see if the drug can shrink tumors. All participants will receive the dru…
Matched conditions: LOCALLY ADVANCED SOLID TUMOR
Phase: PHASE1, PHASE2 • Sponsor: Ipsen • Aim: Disease control
Last updated Mar 24, 2026 12:02 UTC
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New targeted pill tested for Hard-to-Treat cancers
Disease control Recruiting nowThis early-stage study is testing a new oral medication called TNG462, both alone and combined with an existing immunotherapy drug (pembrolizumab), for people with advanced solid tumors that have a specific genetic change called an MTAP deletion. The main goals are to find safe d…
Matched conditions: LOCALLY ADVANCED SOLID TUMOR
Phase: PHASE1, PHASE2 • Sponsor: Tango Therapeutics, Inc. • Aim: Disease control
Last updated Mar 23, 2026 15:20 UTC
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New targeted drug trial offers hope for Tough-to-Treat ROS1 cancers
Disease control Recruiting nowThis clinical trial is testing an experimental drug called zidesamtinib for people with advanced cancers that have a specific genetic change called ROS1. The study aims to find the safest and most effective dose, and then see how well the drug shrinks tumors in patients with ROS1…
Matched conditions: LOCALLY ADVANCED SOLID TUMOR
Phase: PHASE1, PHASE2 • Sponsor: Nuvalent Inc. • Aim: Disease control
Last updated Mar 20, 2026 14:48 UTC
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New weapon against advanced cancer enters human testing
Disease control Recruiting nowThis is the first study in people to test a new drug called NTX-1088, an antibody designed to target a protein found on many cancer cells. The main goals are to find safe doses and see how the body processes the drug, both by itself and when combined with an existing immunotherap…
Matched conditions: LOCALLY ADVANCED SOLID TUMOR
Phase: PHASE1 • Sponsor: Nectin Therapeutics Ltd • Aim: Disease control
Last updated Mar 06, 2026 15:37 UTC
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Face cream trial aims to ease painful side effect of cancer drugs
Symptom relief Recruiting nowThis study is testing if a common acne cream (tretinoin) can prevent or reduce a severe, acne-like rash that is a common and painful side effect of certain cancer drugs. In a unique 'split-face' design, 25 adults with advanced solid tumors will apply the test cream to one side of…
Matched conditions: LOCALLY ADVANCED SOLID TUMOR
Phase: PHASE2 • Sponsor: University of Utah • Aim: Symptom relief
Last updated Mar 30, 2026 14:32 UTC
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New scan aims to see if immunotherapy is working
Knowledge-focused Recruiting nowThis study is testing a new imaging tracer to see if it can help doctors visualize immune cells inside tumors. It involves patients with advanced solid cancers who are about to start a specific type of immunotherapy. The main goal is to see how well the tracer works and if it can…
Matched conditions: LOCALLY ADVANCED SOLID TUMOR
Phase: PHASE2 • Sponsor: University Medical Center Groningen • Aim: Knowledge-focused
Last updated Mar 16, 2026 15:26 UTC