LOCALLY ADVANCED RECTAL CANCER
Clinical trials for LOCALLY ADVANCED RECTAL CANCER explained in plain language.
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New combo therapy aims to shrink rectal tumors before surgery
Disease control Recruiting nowThis study tests two different treatment plans for people with locally advanced rectal cancer that has not spread. Both plans combine radiation, chemotherapy, an immunotherapy drug, and a pain reliever that may boost the immune response. The goal is to see which plan leads to a h…
Matched conditions: LOCALLY ADVANCED RECTAL CANCER
Phase: PHASE2 • Sponsor: Fudan University • Aim: Disease control
Last updated May 15, 2026 11:57 UTC
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Could High-Dose radiation and chemo spare rectal cancer patients from surgery?
Disease control Recruiting nowThis study tests a new approach for people with locally advanced rectal cancer. Participants first receive chemotherapy, then a higher-than-usual dose of precisely targeted radiation. The goal is to see if this combination can eliminate the cancer completely, allowing patients to…
Matched conditions: LOCALLY ADVANCED RECTAL CANCER
Phase: PHASE1 • Sponsor: University of Miami • Aim: Disease control
Last updated May 13, 2026 16:03 UTC
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New study aims to find best treatment for older rectal cancer patients
Disease control Recruiting nowThis study compares two standard treatment approaches for older adults (age 70 and up) with locally advanced rectal cancer. The goal is to see which approach helps people live longer and with fewer side effects. About 230 participants will be randomly assigned to one of the two t…
Matched conditions: LOCALLY ADVANCED RECTAL CANCER
Phase: NA • Sponsor: Jules Bordet Institute • Aim: Disease control
Last updated May 13, 2026 16:00 UTC
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New hope for rectal cancer: combo therapy aims to avoid surgery
Disease control Recruiting nowThis study tests a mix of chemotherapy (CAPOX), an immunotherapy drug (Sintilimab), and short-course radiation that avoids healthy lymph nodes. It is for people with a specific type of advanced rectal cancer (MSS) who want to keep their anus. The goal is to see if the cancer disa…
Matched conditions: LOCALLY ADVANCED RECTAL CANCER
Phase: PHASE2 • Sponsor: Jinhua Central Hospital • Aim: Disease control
Last updated May 13, 2026 15:58 UTC
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New combo therapy aims to shrink rectal tumors and avoid surgery
Disease control Recruiting nowThis study tests whether adding the immunotherapy drug camrelizumab to standard chemoradiotherapy can help shrink tumors completely in people with locally advanced rectal cancer. About 44 adults aged 18-75 with a specific type of rectal cancer (pMMR/MSS) will receive a sequence o…
Matched conditions: LOCALLY ADVANCED RECTAL CANCER
Phase: PHASE2 • Sponsor: Chinese PLA General Hospital • Aim: Disease control
Last updated May 11, 2026 20:50 UTC
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New combo therapy aims to boost complete remission in rectal cancer
Disease control Recruiting nowThis study tests whether adding radiation to a chemotherapy-immunotherapy combination improves outcomes for people with a specific type of advanced rectal cancer (MSS/pMMR). About 192 participants will receive either the drug combo alone or with short-course radiation before poss…
Matched conditions: LOCALLY ADVANCED RECTAL CANCER
Phase: PHASE2 • Sponsor: Fudan University • Aim: Disease control
Last updated May 04, 2026 16:31 UTC
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Can a nutrition drink ease chemo side effects? new study aims to find out
Symptom relief Recruiting nowThis study tests whether a special dietary supplement can reduce severe side effects from standard cancer treatments in people with head and neck, lung, or rectal cancer. About 52 participants will take the supplement during their treatment, and their results will be compared to …
Matched conditions: LOCALLY ADVANCED RECTAL CANCER
Phase: NA • Sponsor: Fondazione del Piemonte per l'Oncologia • Aim: Symptom relief
Last updated May 17, 2026 06:14 UTC
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Cancer Patients' nutrition under the microscope: study aims to improve treatment support
Knowledge-focused Recruiting nowThis study observes 110 adults with head/neck, lung, or rectal cancer to track changes in their nutrition and body composition during standard cancer treatments. Researchers measure daily food intake, muscle mass, and strength over time. The goal is to gather information that wil…
Matched conditions: LOCALLY ADVANCED RECTAL CANCER
Sponsor: Fondazione del Piemonte per l'Oncologia • Aim: Knowledge-focused
Last updated May 17, 2026 06:20 UTC