New combo therapy aims to shrink rectal tumors before surgery

NCT ID NCT07150949

First seen Nov 01, 2025 · Last updated May 15, 2026 · Updated 25 times

Summary

This study tests two different treatment plans for people with locally advanced rectal cancer that has not spread. Both plans combine radiation, chemotherapy, an immunotherapy drug, and a pain reliever that may boost the immune response. The goal is to see which plan leads to a higher chance of the tumor completely disappearing before surgery, possibly allowing some patients to avoid surgery altogether.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Fudan University Shanghai Cancer Center

    RECRUITING

    Shanghai, Shanghai Municipality, 200030, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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