New combo therapy aims to boost complete remission in rectal cancer

NCT ID NCT06281405

First seen Feb 01, 2026 · Last updated May 01, 2026 · Updated 8 times

Summary

This study tests whether adding radiation to a chemotherapy-immunotherapy combination improves outcomes for people with a specific type of advanced rectal cancer (MSS/pMMR). About 192 participants will receive either the drug combo alone or with short-course radiation before possible surgery. The main goal is to see how many achieve a complete response (no cancer detectable).

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Fudan University Shanghai Cancer Center

    RECRUITING

    Shanghai, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.