LIVER TRANSPLANTATION

This study tested whether giving liver transplant patients simple exercise guides (a brochure or a video) helps them become more active, feel less tired, and reduce the burden on their caregivers. 117 adults who had a liver transplant were split into three groups: one got a broch…

This study tested a new way to treat severe blood clots in the portal vein during liver transplant surgery. Doctors used a special approach through a ligament in the donor liver to place stents or close off abnormal veins. The study included 75 patients and found the method safe …

This study tested whether a 12-week exercise program done at home via video calls could help liver transplant patients regain muscle strength, improve exercise ability, and feel less tired. 140 adults who had a liver transplant took part, with half doing the video-supervised exer…

This study tested a method called HOPE, which uses cool, oxygen-rich fluid to preserve donor livers before transplant. It included 266 adults receiving a liver from an older or higher-risk donor. The goal was to see if HOPE reduces early liver problems after surgery compared to s…

This study tested switching children who had stable organ transplants from one immunosuppressant (Prograf) to a longer-acting version (Advagraf). The goal was to compare drug levels in the body and monitor safety and effectiveness over one year, with extended follow-up. 81 childr…

This study tested whether a structured program combining exercise, nutritional advice, and psychological support is safe and doable for frail adults with cirrhosis waiting for a liver transplant. Twenty-five participants were enrolled to see if they could stick with the program a…

This study looked at whether combining physical and mental exercises can help people who have had a liver transplant. 32 adults who were at least 50 years old took part. They did either standard physical therapy or a program that mixed movement with thinking tasks. The goal was t…

This study looked at whether donated livers that were not perfect (called extended criteria donor livers) could be safely used for transplant after being treated with a special machine that pumps fluids through them. The goal was to see if these livers would work well and last a …

This study tested whether very low doses of a protein called IL-2, given as shots under the skin for 4 weeks, could increase the number of helpful immune cells (Tregs) in liver transplant recipients. The goal was to see if this approach might improve the body's acceptance of the …

This study tested whether a short virtual reality session could help patients feel better after a liver transplant. 84 patients were split into two groups: one group used VR for 20 minutes, the other received standard care. Researchers measured pain, fatigue, and vital signs befo…

This study followed 119 caregivers of liver transplant patients to see how their fatigue, burden, and physical activity changed from before transplant to 6 months after. Caregivers completed surveys at three points: before transplant, 90 days after, and 180 days after. The goal i…

This study compared how patients feel about two ways to take a small sample of liver tissue: one using a needle through the skin (percutaneous) and another using a thin tube through the mouth (EUS-guided). 102 adults with chronic liver disease were randomly assigned to one method…

This completed study looked at 3 liver transplant patients to see if muscle loss (sarcopenia) changes how the body responds to the muscle relaxant rocuronium. Researchers measured hand grip strength and used a questionnaire to diagnose sarcopenia before surgery, then tracked how …

This study looked back at data from 484 liver cancer patients who had a liver transplant to see if taking certain cancer drugs (tyrosine kinase inhibitors) before the transplant helped them live longer or kept the cancer from coming back. The researchers checked survival rates, c…

This study looked at 501 adults with severe liver disease (decompensated cirrhosis) who were on the national transplant waiting list. The goal was to create new mathematical models that better predict who is at highest risk of dying while waiting for a liver. By combining known a…

This study tested whether providing free rideshare rides (via Lyft) to liver transplant candidates for all transplant-related medical visits helps them get on the official waiting list faster. 261 adults who had an initial liver transplant clinic visit took part. The study measur…

This study reviewed records of nearly 7,000 liver transplant patients to see if taking statins before surgery lowers the risk of major heart problems like heart attack, stroke, or heart failure. Researchers compared patients who used statins with those who did not. The goal is to…

This study looked at 82 adults getting a liver transplant to see if using a special blood test called ROTEM helps doctors manage bleeding better than standard tests. The goal was to reduce the amount of blood products given during surgery. The study is complete, and results may h…

This study looked at 446 adults who received a first liver transplant to see if changes in their MELD score (a measure of liver disease severity) could predict survival. The goal was to better understand which patients are at higher risk after transplant, especially those with se…