LIVER CANCER

This early-phase study tested a new drug called cabotamig in 33 adults with advanced gastrointestinal cancers (like colon, stomach, liver, or pancreatic cancer) that had stopped responding to standard treatments. The drug works by attaching to a marker on cancer cells and helping…

This study tested a precise type of radiation called proton beam therapy for people with liver cancer that could not be removed by surgery. The goal was to see if this focused radiation could kill cancer cells while causing fewer side effects than standard radiation. 83 adults wi…

This early-phase study tested a custom-made yeast vaccine designed to teach the immune system to recognize and attack leftover cancer cells. Five adults with different solid tumors (like colorectal, breast, or lung cancer) who had already completed curative treatment received the…

This early-stage study tested a new drug (BI 765049) alone or with another drug (ezabenlimab) in 21 Asian adults with advanced solid tumors like lung, stomach, or liver cancer. The goal was to find a safe dose and see if the drugs could shrink tumors. Participants received infusi…

This study tested a new combination treatment for people with liver cancer that cannot be removed by surgery. The treatment involved infusing chemotherapy directly into the liver, followed by a procedure to block the tumor's blood supply, plus two oral and intravenous drugs. The …

This study tested two chemotherapy drugs, cisplatin and mitomycin-C, given directly into the liver artery for people with liver cancer that cannot be surgically removed. The goal was to see how long it takes for tumors to grow and to monitor side effects. The study also looked at…

This study tested whether a shortened MRI scan (AMRI) works better than standard ultrasound for finding liver cancer early in people with liver cirrhosis. Researchers compared how accurately each method detected cancer in 79 participants. The goal is to see if AMRI can be a more …

This study tested a special ultrasound (CEUS) that uses a contrast dye to get clearer images of liver spots found on regular ultrasound. The goal was to see if CEUS can accurately tell if a spot is cancerous or not, potentially avoiding the need for more expensive or invasive tes…

This study looked for new substances in the blood that could help diagnose liver cancer more accurately. Researchers tested blood samples from 573 people, including those with liver cancer, other liver diseases, and hepatitis infections. The goal is to improve upon current tests …

This study tested whether giving lidocaine through a vein during liver surgery can reduce pain and the need for strong painkillers (opioids) afterward. 124 adults having minor liver surgery were randomly assigned to receive either lidocaine or a placebo (salt water) during the op…

This study tested a new type of CT scanner that takes pictures during radiation therapy for lung, liver, breast, and other cancers. The goal was to see if the new scanner produces clearer images with fewer distortions. 31 people participated, and the results will help doctors bet…

This study looked at whether liver cancer spreads differently in men and women. Researchers analyzed data from over 19,000 patients and used machine learning to create separate prediction tools for each gender. The goal was to better understand which factors predict cancer spread…

This study is a registry that collected information on how SIR-Spheres (tiny radioactive beads) are used in real-world medical practice to treat liver cancer in France. Over 300 adults with primary or secondary liver tumors were included. The goal was to describe the treatment co…

This study created a worldwide registry for people with fibrolamellar cancer (FLC), a rare liver cancer. Researchers collected information from 12 participants about their medical history and routine care. The goal was to build a database that can be used for future studies. No t…

This study tested whether a simple breath analysis could help diagnose or predict liver disease, liver cancer, and COVID-19. Researchers collected breath samples from 46 participants to detect unique chemical patterns. The goal was to develop a non-invasive test for disease diagn…

This study looked at whether tracking changes in blood markers over time, along with patient health details, can better predict how liver cancer will progress. Researchers analyzed data from 379 patients to build a model that helps doctors estimate risk and personalize treatment.…

This study looked at 52 adults who had a living donor liver transplant to see if using a microscope or surgical loupes (magnifying glasses) for bile duct repair leads to fewer complications. The goal was to find out which tool works better for this delicate step. Results will hel…