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New ultrasound technique could spare liver patients from costly scans and needles

NCT ID NCT00243633

Completed Diagnosis Sponsor: University Hospital, Tours Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether a special ultrasound with contrast dye (CEUS) can more accurately identify liver lesions than standard ultrasound or other imaging methods like CT and MRI. Researchers enrolled 878 participants with liver lesions found on standard ultrasound. The goal was to see if CEUS could provide a reliable diagnosis without needing invasive biopsies, potentially saving costs and discomfort.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Contrast-enhanced ultrasound (CEUS) imaging
What this could lead to
If successful, CEUS could become a standard, non-invasive way to accurately diagnose liver lesions, reducing the need for more expensive or invasive tests like CT, MRI, or biopsy.
What could go wrong
This is a completed study, so results are already known. The main risk is that CEUS may not be accurate enough for all types of liver lesions, and it cannot be used in patients with certain heart conditions.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cirrhosis of liver Fibrosis liver cancer Liver Neoplasms

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

FOCAL LIVER LESIONS LIVER CANCER LIVER CIRRHOSIS

Contacts and locations

Locations

  • CHRU d'ANGERS

    Angers, 49033, France

  • Hospices Civils de Lyon

    Lyon, 69003, France

  • Hôpital Beaujon, Assistance Publique Hôpitaux de Paris

    Clichy, 92118, France

  • Hôpital Bretonneau, CHRU Tours

    Tours, 37044, France

  • Hôpital La Milétrie, CHRU Poitiers

    Poitiers, 86000, France

  • Hôpital Necker, Assistance Publique Hôpitaux de Paris

    Paris, 75743, France

  • Hôpital Nord, CHRU Saint-Etienne

    Saint-Etienne, 42055, France

  • Hôpital Paul Brousse, Assistance Publique Hôpitaux de Paris

    Villejuif, 94804, France

  • Hôpital Pitié Salpétrière, Assistance Publique Hôpitaux de Paris

    Paris, 75651, France

  • Hôpital Robert Debré, CHRU Reims

    Reims, 51092, France

  • Hôpital Saint-André, CHRU Bordeaux

    Bordeaux, 33075, France

  • Hôpital Saint-Eloi, CHRU Montpellier

    Montpellier, 34295, France

  • Hôpital Saint-Jacques, CHRU Besancon

    Besançon, 25000, France

  • Institut Gustave Roussy

    Villejuif, 94805, France

  • Service de Radiologie, Hôpital d'Enfants de Brabois

    Vandœuvre-lès-Nancy, 54511, France

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