LEIOMYOSARCOMA
Clinical trials for LEIOMYOSARCOMA explained in plain language.
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Immunotherapy duo shows promise in early sarcoma trial
Disease control OngoingThis early-phase study tests whether adding an experimental drug (BO-112) to the immunotherapy nivolumab before surgery can help treat soft tissue sarcoma. About 14 adults with removable tumors will receive the combination to check for side effects and immune changes. The goal is…
Matched conditions: LEIOMYOSARCOMA
Phase: PHASE1 • Sponsor: Jonsson Comprehensive Cancer Center • Aim: Disease control
Last updated May 17, 2026 04:28 UTC
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New cell therapy takes on Epstein-Barr virus in patients with weak immune systems
Disease control OngoingThis study tests an experimental cell therapy called tabelecleucel in about 190 people with diseases caused by the Epstein-Barr virus (EBV). The treatment uses specially trained immune cells to attack EBV-infected cells. The main goal is to see if the therapy can shrink tumors or…
Matched conditions: LEIOMYOSARCOMA
Phase: PHASE2 • Sponsor: Pierre Fabre Medicament • Aim: Disease control
Last updated May 17, 2026 04:26 UTC
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New combo therapy shows promise for rare cancer
Disease control OngoingThis study tests whether combining two drugs, rucaparib and nivolumab, can effectively treat advanced or metastatic leiomyosarcoma (LMS), a rare cancer of smooth muscle. About 20 adults with unresectable or metastatic LMS who have had at least one prior treatment will receive the…
Matched conditions: LEIOMYOSARCOMA
Phase: PHASE2 • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Disease control
Last updated May 15, 2026 12:06 UTC
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Virus and radiation team up against sarcoma
Disease control OngoingThis study tests a combination of a cancer-killing virus (T-VEC) and radiation therapy in 40 adults with newly diagnosed soft tissue sarcoma that can be surgically removed. The goal is to see if this approach destroys more tumor cells before surgery and to check for side effects.…
Matched conditions: LEIOMYOSARCOMA
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 13, 2026 16:03 UTC
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New combo therapy aims to shrink sarcomas before surgery
Disease control OngoingThis study looks at whether adding the drug pazopanib to standard radiation or chemoradiation helps shrink soft tissue sarcomas before they are removed surgically. About 140 adults and children with newly diagnosed, high-risk sarcomas that can be operated on are participating. Th…
Matched conditions: LEIOMYOSARCOMA
Phase: PHASE2, PHASE3 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 13, 2026 16:02 UTC
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New study explores drug cocktails for Hard-to-Treat cancers
Knowledge-focused OngoingThis study tests two drug combinations in people with advanced colorectal, pancreatic, or leiomyosarcoma cancers that have not responded to standard treatments. Participants receive either olaparib plus durvalumab or cediranib plus durvalumab. The main goal is to measure changes …
Matched conditions: LEIOMYOSARCOMA
Phase: PHASE2 • Sponsor: University Health Network, Toronto • Aim: Knowledge-focused
Last updated May 17, 2026 04:25 UTC