LEIOMYOSARCOMA
Clinical trials for LEIOMYOSARCOMA explained in plain language.
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Virus therapy teams up with radiation to fight sarcoma
Disease control OngoingThis study is testing a two-part treatment for soft tissue sarcoma that can be removed by surgery. First, doctors inject a modified cold sore virus (T-VEC) directly into the tumor to help the immune system attack the cancer. Then, patients receive a standard course of radiation t…
Matched conditions: LEIOMYOSARCOMA
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Mar 31, 2026 12:12 UTC
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Scientists test new drug cocktails in fight against tough cancers
Disease control OngoingThis study is testing two different drug combinations to see how they affect advanced cancers that have stopped responding to standard treatments. It will enroll about 90 people with specific types of advanced colorectal cancer, pancreatic cancer, or a soft tissue sarcoma. The ma…
Matched conditions: LEIOMYOSARCOMA
Phase: PHASE2 • Sponsor: University Health Network, Toronto • Aim: Disease control
Last updated Mar 27, 2026 12:37 UTC
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Two-Drug combo tested for Tough-to-Treat rare cancer
Disease control OngoingThis study is testing whether combining two drugs, rucaparib and nivolumab, can help control advanced leiomyosarcoma (LMS), a rare type of cancer. It is for adults whose cancer has spread or cannot be removed by surgery and who have tried 1 to 3 other treatments. The main goal is…
Matched conditions: LEIOMYOSARCOMA
Phase: PHASE2 • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Disease control
Last updated Mar 27, 2026 12:37 UTC
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New hope for tough sarcomas: adding a targeted drug to standard treatment
Disease control OngoingThis study is for patients with newly diagnosed, high-risk soft tissue sarcomas that can be removed by surgery. It tests whether adding a drug called pazopanib to standard pre-surgery treatments (radiation with or without chemotherapy) helps shrink tumors more effectively and imp…
Matched conditions: LEIOMYOSARCOMA
Phase: PHASE2, PHASE3 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Mar 25, 2026 14:09 UTC
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New Two-Pronged attack tested against rare cancers before surgery
Disease control OngoingThis early-stage study is testing the safety of combining two immunotherapy drugs, nivolumab and BO-112, given before surgery for patients with operable soft tissue sarcoma. The goal is to see if stimulating the immune system to attack the tumor before it is removed can improve o…
Matched conditions: LEIOMYOSARCOMA
Phase: PHASE1 • Sponsor: Jonsson Comprehensive Cancer Center • Aim: Disease control
Last updated Mar 24, 2026 12:02 UTC