KIDNEY STONES

This study tests a new device called the CVAC system that uses suction during a scope procedure to remove kidney stones. It compares how well this works versus the usual method (laser and no suction) in 150 adults. The main goal is to see if the new tool leaves fewer stone fragme…

This trial compares two surgical techniques for removing large or complex kidney stones: a modified mini version using a smaller access sheath (20 Fr) versus the standard approach (24 Fr). The goal is to see if the mini procedure causes less bleeding and pain while still clearing…

This study compares two laser systems—thulium fiber laser and pulsed Thulium:YAG—for breaking up kidney stones during a procedure called ureteroscopy. Researchers will measure how much energy each laser uses per stone volume and how fast it works. The goal is to find which laser …

This study compares two types of lasers used to break up kidney stones during a minimally invasive procedure called ureteroscopy. One laser uses a superpulse thulium fiber (sTFL), the other is a standard holmium laser. Researchers will enroll 136 adults aged 18–70 with kidney sto…

This study is testing whether a simple, standard prevention plan works as well as a personalized one for people who get calcium oxalate kidney stones. 80 participants will either receive a diuretic and diet advice based on their stone type alone, or have their treatment guided by…

This study tests whether empagliflozin, a drug used for diabetes and heart conditions, can help prevent calcium-based kidney stones. Researchers will give the drug daily for 4 weeks to 32 adults who have had calcium oxalate or calcium phosphate stones. They will measure changes i…

This study compares two types of tubes used during surgery to remove kidney stones. One tube uses suction (vacuum) to help clear stone fragments, while the other is a standard tube. The goal is to see which tube is safer and more effective at removing all stone pieces. About 150 …

This study compares two versions of a shockwave machine for breaking kidney stones: one with stone tracking and one without. About 126 adults with a single kidney stone (6-15 mm) will be randomly assigned to either group. The goal is to see if the tracking feature helps more peop…

This study tests two different tubes used during kidney stone surgery to see which one works better. One tube has suction to remove stone pieces and fluid, while the other does not. Researchers will track how many patients are stone-free after surgery and compare complication rat…

This study compares a new, thinner flexible scope (HugeMed 6.3 French) to standard scopes for removing kidney stones up to 2.5 cm. Researchers want to see if the new scope saves money while still clearing stones just as well. About 75 adults with kidney or ureter stones will take…

This study compares two common surgeries for removing kidney stones: mini-PCNL (a small incision in the back) and flexible ureteroscopy with a special suction tube. About 80 adults with kidney stones between 1 and 3 cm will be randomly assigned to one procedure. The main goal is …

This study tests a simple change during kidney stone surgery: actively suctioning the kidney to collapse it at the end of the procedure, instead of letting it drain naturally. Researchers want to see if this reduces pain and infection right after surgery. About 90 adults with kid…

This study tests whether taking the steroid prednisone after ureteroscopy (a surgery for kidney stones) can help reduce pain and the need for other pain medications. Researchers will enroll 90 adults who are having this surgery with a stent placed. The goal is to see if adding a …

This study aims to find out if people who get calcium oxalate kidney stones produce more oxalate in their bodies than healthy people. Researchers will compare 80 adults—some with a history of stones and some without—after they eat a special low-oxalate diet and take small amounts…

This study tests a new training tool for kidney stone surgery. Trainee surgeons wear augmented reality goggles that show them where an expert surgeon is looking during the operation. The goal is to help trainees learn to explore the kidney more completely, which could reduce the …

This study aims to understand how oxalate, a substance found in many foods, contributes to kidney stone formation and affects the body's immune system. Researchers will enroll 88 healthy volunteers and people with calcium oxalate kidney stones. Participants will follow a controll…

This study looks at whether using a special suction device during kidney stone surgery can reduce how much irrigation fluid gets absorbed into the body and lower the risk of infections. Researchers will compare 400 adults who have surgery with or without the suction sheath. The g…