KIDNEY STONES

This study tests a new device that combines a camera and suction in one tool for kidney stone removal surgery. About 75 adults with kidney stones between 0.5 and 2.0 cm will undergo the procedure to see if the device safely clears stones and reduces leftover fragments. The goal i…

This trial tests four different breathing strategies during kidney stone surgery to see if reducing kidney motion helps surgeons remove stones more completely and lowers the risk of complications. Eighty adults undergoing the procedure will be randomly assigned to standard ventil…

This study compares two suction-assisted techniques used during minimally invasive kidney stone surgery. The goal is to see which method better clears stones and lowers the risk of infection. About 126 adults with medium-sized kidney stones (2-3 cm) will be randomly assigned to o…

This study compares a new tool called the CVAC system, used with a special scope, to standard treatments for removing kidney stones. About 1,000 adults who need stone removal will be randomly assigned to either the new method or usual care. The main goal is to see if the new appr…

This trial tests a new way to remove kidney stones using a special laser and a flexible suction sheath. 140 adults with stones between 6mm and 20mm will be randomly assigned to get the new suction sheath or a standard sheath. The goal is to see if the new method clears more stone…

This study compares two common procedures—flexible ureteroscopy (a scope through the urinary tract) and shock wave lithotripsy (sound waves to break stones)—for treating small kidney stones (≤15 mm) located in the lower calyx. Researchers will enroll 70 adults and check which met…

This study tests three common pain relievers (ibuprofen, paracetamol, and tenoxicam) against a placebo to see which works best during shock wave treatment for kidney stones. About 160 adults will rate their pain at several points during the procedure. The goal is to find the safe…

This study compares two new suction-based tools (FANS and CVAC) for removing medium-to-large kidney stones. About 159 adults with stones 8-20 mm will be randomly assigned to one device. The goal is to see which scope clears more stones completely, as shown on CT scans.

This study compares two nerve block techniques—dual external oblique fascial plane block and erector spinae plane block—for pain control after percutaneous nephrolithotomy (PCNL), a surgery to remove large kidney stones. Ninety adults will be randomly assigned to receive one of t…

This study tests a new robotic system called LARC that helps surgeons precisely guide a needle into the kidney during surgery for large kidney stones. The goal is to make the procedure safer and faster by reducing the need for a separate pre-surgery step. Up to 45 adults will be …

This study will test whether taking apple cider vinegar every day for a short time changes the chemistry of urine in adults, both those with a history of calcium oxalate kidney stones and healthy volunteers. Researchers will measure levels of citrate, pH, calcium, and calcium oxa…

This pilot study tests a patient navigation program for people who visited the ER for kidney stones and are at risk of missing their follow-up urology appointment. About 31 participants will get a trained navigator who helps with scheduling, transportation, and other barriers for…

This study will compare gut bacteria and blood markers between 270 kidney stone patients and healthy people in Shanghai. Researchers want to see if hot, humid weather changes gut microbes and tryptophan metabolism in ways that promote stone formation. No treatment is given; the g…