INFECTION

This study compared two ways to perform a prostate biopsy: the standard transrectal method (through the rectum) and a newer transperineal method (through the skin between the scrotum and anus). The goal was to see which method causes fewer infections. Over 1,000 men participated,…

This study tested three different nutrition plans given through a feeding tube after surgery for head and neck cancer. The goal was to see which plan best prevents infections. The trial included 311 adults scheduled for tumor removal. Results help guide post-surgery care to reduc…

This study tested whether using a suction toothbrush for oral care can lower the chance of ventilator-associated pneumonia (VAP) in intubated ICU patients. Researchers compared the suction toothbrush to standard care in 111 adults on breathing machines. The goal was to see if bet…

This study tested whether a simple saltwater mouth rinse can detect pneumocystis, a lung infection that can be life-threatening for people with weak immune systems (like those with HIV, cancer, or organ transplants). Current diagnosis requires coughing up lung fluid or a tube ins…

This study tested a simple strip test called PeriScreen to quickly diagnose infections in the belly fluid of people with cirrhosis. The goal was to see if the strip could detect infection as accurately as standard lab tests, but much faster. Researchers studied 649 patients and c…

This study tested whether installing far-UVC lamps in nursing homes can reduce hospitalizations caused by infections like pneumonia and urinary tract infections. About 635 residents in 12 Danish care homes took part, with some homes receiving the lamps in common areas or apartmen…

This study tested whether putting vancomycin powder directly into the surgical wound during brain surgery can prevent infections. Over 1100 adults having neurosurgery were randomly assigned to receive either the standard care or standard care plus topical vancomycin. Researchers …

This study looked at a new single-use duodenoscope (aScope) in 59 patients at high risk for infection after an ERCP procedure. The goal was to see if the disposable scope could successfully complete the procedure and reduce infection risks linked to standard reusable scopes. Rese…

This study looked at 275 adults with a lung condition called bronchiectasis, where airways are stretched and trap mucus, leading to infections. The goal was to better describe the physical traits, lung scans, and germs in the lungs of people with no known cause. Participants gave…

This study looked at 196 people who had jaw-lengthening surgery to fix jaw problems. Researchers wanted to see if using a special bone paste (calcium phosphate) caused more infections or the need to remove metal plates. They also checked if the paste's benefits—like better stabil…

This study looked at data from 372 patients who were part of a home hospital program. Researchers used a computer program (machine learning) to see if it could predict which patients would need to be readmitted to the hospital within 30 days. The goal was to learn if this approac…

This study looked at two different ways of giving the antibiotic cloxacillin to 12 people with bone and joint infections caused by Staphylococcus aureus bacteria. The goal was to see if giving the drug continuously or in short bursts worked equally well. Researchers measured drug…

This study checked if testing patients for certain drug-resistant bacteria (called MDR gram-negative organisms) when they enter the hospital can predict if they will later get an infection from those same germs. Researchers looked back at records of nearly 2,900 adult patients wh…

This study looked at whether a computer program could predict when patients being treated at home might suddenly get worse. Researchers used data from 526 patients to train and test the program. The goal was to see if the program could alert doctors early, helping prevent serious…

This study looked at how the immune system responds to a harmless part of the cholera toxin when given through the mouth, nose, or under the tongue. It involved 40 healthy adults aged 18 to 50. The goal was to understand immune reactions better, which could help in designing futu…

This study compared two methods of prostate biopsy in 840 men who needed the procedure due to suspected prostate cancer. One method goes through the rectal wall, the other through the skin between the scrotum and anus. The goal was to see which approach causes fewer infections an…

This study tested a new rapid diagnostic tool to quickly identify antibiotic-resistant bacteria in wounded warriors and veterans. Over 2,200 participants provided samples from skin, blood, or lungs. The goal was to see if the new method could accurately guide antibiotic choice be…