Which prostate biopsy method is safer and better at finding cancer?

NCT ID NCT04081636

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compared two common methods for taking a prostate biopsy: one through the rectal wall and one through the skin between the scrotum and anus. 840 men who needed a biopsy for suspected prostate cancer were randomly assigned to one of the two methods. The goal was to see which approach causes fewer infections and detects more significant cancers.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If this trial succeeds, doctors may know which biopsy method is safer and more accurate for diagnosing prostate cancer.

What could go wrong

This is a completed study comparing two standard procedures, not a new treatment. Results may not change practice if neither method is clearly superior.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Hemorrhage Infections infectious disease pleomorphic adenoma prostate cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Albany Medical College

    Albany, New York, 12208, United States