HODGKIN LYMPHOMA

This large, completed study compared two different chemotherapy combinations for adults with newly diagnosed, advanced Hodgkin lymphoma. Over 1,300 patients were randomly assigned to receive either the standard treatment (ABVD) or a newer regimen (A+AVD) that included a targeted …

This early-stage study aimed to find a safe dose of a new drug combination (BMS-986345 plus duvelisib) for patients with advanced blood cancers like lymphoma and leukemia. It involved 14 adults whose cancers had progressed after other treatments. The main goal was to check for si…

This small pilot study tested whether an 8-week home exercise program delivered via video calls is practical and helpful for lymphoma survivors. The goal was to see if regular, guided workouts could improve heart health and reduce future cardiovascular risks in people who had fin…

This study tested whether adding the immunotherapy drug pembrolizumab after a patient's own stem cell transplant could help keep certain aggressive lymphomas from returning. It involved 82 adults with Hodgkin lymphoma, diffuse large B-cell lymphoma, or T-cell lymphoma that had co…

This study tested the safety and early effectiveness of combining two immunotherapy drugs, nivolumab and daratumumab, for people with multiple myeloma that has returned or stopped responding to standard treatments. It involved about 320 participants with various blood cancers, fo…

This early-stage study tested the safety and initial effectiveness of combining two drugs, acalabrutinib and pembrolizumab, for people with various blood cancers. It involved 161 participants with conditions like lymphoma and leukemia. The main goal was to see if the combination …

This study aimed to find the best strategy for finding bone marrow transplant donors for patients with blood cancers and disorders. It compared whether patients should first search for a perfectly matched unrelated donor or go directly to alternative donors like family members or…

This study tested a less intense bone marrow transplant procedure for adults with various blood cancers who needed a transplant but did not have a fully matched donor. It used stem cells from a half-matched family member (like a parent, child, or sibling) after a milder pre-trans…

This study tested whether a new two-drug combination (favezelimab/pembrolizumab) could help people with classical Hodgkin lymphoma live longer without their cancer getting worse, compared to standard chemotherapy. It focused on patients whose cancer had returned or stopped respon…

This study compared two different drugs for people whose Hodgkin lymphoma returned or didn't respond to previous treatment. Researchers tested whether pembrolizumab (an immunotherapy drug) worked better than brentuximab vedotin (a targeted therapy) at keeping the cancer from prog…

This study tested a two-step, lower-intensity stem cell transplant for patients with high-risk blood cancers like leukemia and lymphoma. The goal was to use milder chemotherapy and radiation before the transplant to reduce side effects while still allowing the donor's immune cell…

This study aimed to understand why patients with the same type of blood cancer, like lymphoma or leukemia, can have very different outcomes. Researchers analyzed the genes in old tissue samples from 1,340 patients to see if they could find patterns that predict how the disease wi…