New combo therapy shows promise for Hard-to-Treat blood cancers
NCT ID NCT02362035
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested a combination of two drugs, acalabrutinib and pembrolizumab, in 161 people with various blood cancers such as lymphoma, leukemia, and multiple myeloma. The main goal was to check safety and side effects, while also seeing if the tumors shrank. The approach aims to control the disease rather than cure it, as ongoing treatment may be needed.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Research Site
Tucson, Arizona, 85704, United States
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Research Site
Los Angeles, California, 90095, United States
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Research Site
Denver, Colorado, 80218, United States
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Research Site
Washington D.C., District of Columbia, 20007, United States
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Research Site
Niles, Illinois, 60714, United States
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Research Site
Boston, Massachusetts, 2215, United States
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Research Site
Rochester, Minnesota, 55905-0001, United States
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Research Site
Omaha, Nebraska, 68198-7680, United States
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Research Site
Columbus, Ohio, 43210, United States
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Research Site
Greenville, South Carolina, 29605, United States
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Research Site
Nashville, Tennessee, 37203, United States
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Research Site
Dallas, Texas, 75246, United States
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Research Site
Houston, Texas, 77030, United States
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Research Site
San Antonio, Texas, 78217, United States
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Research Site
Tyler, Texas, 75702, United States
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Research Site
Fairfax, Virginia, 22031, United States
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Research Site
Roanoke, Virginia, 24014, United States
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Research Site
Vancouver, Washington, 98684, United States
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Research Site
Yakima, Washington, 98902, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Can a Three-Drug cocktail replace chemo for follicular lymphoma?
- Can a Two-Drug combo beat back Tough-to-Treat hairy cell leukemia?