HIV PREVENTION

This study looks at whether adding a peer health coach to re-entry services can help people with a history of incarceration learn about and start taking PrEP, a daily pill that prevents HIV. About 100 adults in Dallas who use Unlocking Doors services will take part. The goal is t…

This study looks at whether two HIV prevention methods—a long-acting shot and daily pills—are safe for pregnant women and their infants in Malawi. About 621 pregnant women already using or starting HIV prevention will choose either the shot or pills and be followed through pregna…

This study is testing a new approach called PAC-Man to help prevent HIV transmission from mothers to their babies in Malawi. About 2,426 mothers and infants will take part to see if this model improves timely HIV testing and viral load checks compared to standard care. The goal i…

This study tests an online program called UPDOs Protective Styles to help Black women in the southeastern US learn about and start using PrEP, a daily pill that prevents HIV. About 1000 women from 32 beauty salons will either use the program (videos, blogs, and telehealth) or rec…

This study tests a program called MEPS that uses a mobile app, peer mentors, and incentives to help people recently released from jail access HIV prevention (like PrEP), STI testing, and substance use treatment. About 300 people across three California counties will take part. Th…

This study tests a mobile van that offers HIV and STI testing to men who have sex with men (MSM) in Baltimore, recruited through online spaces. Participants get either a peer health navigator to help them start PrEP or HIV care, or just a referral. The goal is to see if the navig…

This study tests a new data dashboard to help clinics in Alabama better track and improve HIV prevention services (PrEP). Researchers will work with seven clinics to see if the dashboard helps more Black and other at-risk people get PrEP prescriptions. The study involves clinic s…

This study looks at how a one-time dose of two F/TAF tablets (a common HIV prevention pill) works in the body over 14 days. It involves 24 healthy volunteers to measure drug levels inside cells. The goal is to see if a higher single dose could be a simpler way to prevent HIV.

This study tests a new way to prevent HIV by giving a long-acting injectable medication called lenacapavir to people who are unhoused or unstably housed in Los Angeles County. A mobile health van brings the shots directly to shelters, encampments, and community centers. The goal …

This study tests three approaches to help 600 teen girls and young women (ages 15-24) at high risk of HIV in Uganda start and stick with PrEP, a daily pill that prevents HIV. Some participants get HIV risk education alone, others add peer support from PrEP users, and a third grou…

This study is testing a special harm reduction service designed for transgender women, men, and non-binary people in Thailand who use substances or engage in chemsex. The goal is to increase use of HIV prevention pills (PrEP), reduce sexually transmitted infections, and improve m…

This study tests a program that gives HIV self-test kits and counseling to new mothers in South Africa whose partners' HIV status is unknown. The goal is to help women start PrEP (a daily pill to prevent HIV) and help partners who test positive get treatment. The study involves 1…

This study tests a program called Treat4All that helps people who drink heavily and are at risk for HIV or already have HIV. About 160 adults in Lilongwe, Malawi will either get the program or usual care. The goal is to see if it reduces heavy drinking and increases HIV preventio…

This study tests a program to help Black women in Baltimore start taking PrEP, a medicine that prevents HIV. The program addresses challenges like intimate partner violence and racism that can make it hard to get PrEP. About 300 Black women who are HIV-negative and at risk will t…

This study is tracking how HIV prevention works in real life across 23 clinics in France. It will enroll 6500 HIV-negative adults to look at screening, PrEP, and PEP. The goal is to understand who uses these services and how well they work.

This study tests a culturally-tailored program offering long-acting injectable PrEP (lenacapavir) to Latine gay, bisexual men and transgender women. The goal is to see if this community-delivered approach helps more people stay on PrEP compared to standard clinic care. Participan…

This study looks at how to help cisgender women and transgender individuals, especially Black and Latinx communities, use PrEP (a daily pill that prevents HIV). Researchers will survey 175 participants about their preferences and challenges with PrEP. The goal is to find better w…

This study tests a mobile health program designed to reduce HIV-related stigma and improve use of HIV prevention pills (PrEP) among young transgender women in Thailand. About 108 HIV-negative participants aged 18-29 who have had condomless sex will use the app and be followed for…

This study tests a text-message-based program to help trans girls and nonbinary youth (ages 14-18) prevent HIV. Participants receive messages and surveys on their phones to encourage HIV testing and use of PrEP (a daily pill that prevents HIV). The goal is to see if this approach…

This study talks to men who have sex with men and take part in chemsex (using drugs during sex) in Bangkok. Researchers want to learn about the risks, health problems, and needs of these men. The goal is to create a program where party hosts help reduce harm, like preventing HIV …

This study looks at whether adding conversations about sexual pleasure to existing harm reduction services helps men who have sex with men and transgender people who use drugs during sex. Researchers will use a tool called the Pleasuremeter to measure sexual pleasure and see how …

This study looks at whether people with HIV can collect their own blood samples at home using a simple finger prick. The goal is to see if these home samples give the same results as clinic blood draws for measuring HIV drug levels. About 150 adults already taking HIV treatment o…

This study talks to transgender people about their experiences with chemsex (using drugs during sex) to learn why they do it, the good and bad effects, and what kind of help they need. Researchers will also ask healthcare workers and community leaders about barriers to providing …