HIV-1-INFECTION
Clinical trials for HIV-1-INFECTION explained in plain language.
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HIV patients may ditch daily pills for Every-Other-Month shots
Disease control Not yet recruitingThis study looks at whether people with HIV who are already well-controlled on daily pills can switch to a long-acting injection given every 2 months. The goal is to see how many stay on the shots without stopping or needing to change treatment over 48 weeks. About 200 adults wit…
Matched conditions: HIV-1-INFECTION
Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Disease control
Last updated May 17, 2026 03:14 UTC
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Can antibodies keep HIV in check without daily pills?
Disease control Not yet recruitingThis early-stage study tests whether two lab-made antibodies can safely control HIV when participants pause their regular antiretroviral therapy (ART). The study involves 40 people with HIV who started treatment very early after infection. Researchers will monitor side effects an…
Matched conditions: HIV-1-INFECTION
Phase: PHASE1 • Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) • Aim: Disease control
Last updated May 17, 2026 03:08 UTC
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New HIV pill aims to control virus fast in untreated patients
Disease control Not yet recruitingThis study tests a three-drug pill (doravirine, lamivudine, tenofovir) for people newly diagnosed with HIV who have never taken HIV medication. The goal is to see if starting treatment quickly can lower the virus to undetectable levels by 48 weeks. About 100 adults will take the …
Matched conditions: HIV-1-INFECTION
Phase: PHASE4 • Sponsor: Fundación Huésped • Aim: Disease control
Last updated May 12, 2026 13:41 UTC
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New study tests cheaper chemo options for HIV cancer in africa
Disease control Not yet recruitingThis study compares two chemotherapy drugs, paclitaxel and pegylated liposomal doxorubicin, to see if they work similarly well for treating Kaposi sarcoma in people with HIV. The trial will enroll 130 participants in sub-Saharan Africa, giving each drug once every three weeks for…
Matched conditions: HIV-1-INFECTION
Phase: PHASE3 • Sponsor: AIDS Malignancy Consortium • Aim: Disease control
Last updated May 11, 2026 20:53 UTC
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Can Same-Day HIV med restart help patients get back on track?
Disease control Not yet recruitingThis study looks at whether people with HIV who have stopped taking their medication for at least 12 weeks can safely restart treatment on the same day they return to care. About 200 adults will receive a once-daily pill (B/F/TAF) and be monitored for viral suppression and side e…
Matched conditions: HIV-1-INFECTION
Phase: PHASE4 • Sponsor: CAN Community Health • Aim: Disease control
Last updated May 05, 2026 11:55 UTC
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New cocktail aims to flush out and destroy hidden HIV
Disease control Not yet recruitingThis early-stage trial tests whether a combination of three existing drugs (topiramate, lenalidomide, and pyrimethamine) can wake up dormant HIV hiding in the body and then help the immune system eliminate those infected cells. The goal is to reduce the hidden HIV reservoir, movi…
Matched conditions: HIV-1-INFECTION
Phase: PHASE1, PHASE2 • Sponsor: Erasmus Medical Center • Aim: Disease control
Last updated May 05, 2026 11:55 UTC
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Scientists give meth to HIV patients to unlock Virus's hiding spots
Knowledge-focused Not yet recruitingThis study looks at how short-term methamphetamine use affects the hidden HIV virus in people who are already on effective HIV medication. About 20 adults with well-controlled HIV will take oral methamphetamine under medical supervision. Researchers will measure changes in the vi…
Matched conditions: HIV-1-INFECTION
Phase: PHASE4 • Sponsor: University of California, San Francisco • Aim: Knowledge-focused
Last updated May 17, 2026 03:19 UTC
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Can a nurse-led plan help HIV patients stick to blood pressure meds?
Knowledge-focused Not yet recruitingThis study aims to understand why people with HIV who have controlled their virus sometimes struggle to take their blood pressure medications. Researchers will interview patients and providers, then design and test a nurse-led support program. The goal is to improve heart health …
Matched conditions: HIV-1-INFECTION
Phase: NA • Sponsor: Duke University • Aim: Knowledge-focused
Last updated May 15, 2026 11:55 UTC