HIV shots tested in pregnancy: a step toward easier treatment for moms

NCT ID NCT07637942

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at how long-acting injectable HIV drugs (cabotegravir and rilpivirine) work in the body during pregnancy and after childbirth. About 40 pregnant women with HIV will receive the shots every 4 weeks. The goal is to measure drug levels and see if they stay effective, helping to keep the mother healthy and reduce the risk of passing HIV to the baby.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Long-acting injectable cabotegravir and rilpivirine

What this could lead to

If successful, this could show that long-acting HIV shots work well during pregnancy, offering a convenient option for pregnant women with HIV.

What could go wrong

This is a small, early-phase study (40 participants) focused on drug levels, not on proving the drugs prevent HIV transmission. Results may not apply to all women, and there are unknown risks during pregnancy.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

HIV infectious disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Site 4001, Lurie Children's Hospital of Chicago CRS

    Chicago, Illinois, 60614, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Site 4601, University of California, UC San Diego CRS

    La Jolla, California, 92093, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Site 5013, Jacobi Medical Center Bronx

    The Bronx, New York, 10461, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Site 5030, Emory University School of Medicine

    Atlanta, Georgia, 30322, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Site 5048, University of Southern California

    Los Angeles, California, 90033, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Site 5052, University of Colorado

    Aurora, Colorado, 80045, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Site 5092, Johns Hopkins University

    Baltimore, Maryland, 21287, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Site 5128, Baylor College of Medicine/Texas Children's Hospital

    Houston, Texas, 77030, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Site 6201, University of Pennsylvania

    Philadelphia, Pennsylvania, 19104, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Site 6501, St Jude Children's Research Hospital

    Memphis, Tennessee, 38105, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••