Can methamphetamine help uncover hidden HIV? a new study investigates

NCT ID NCT07584369

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study will give a single dose of oral methamphetamine to 20 people with HIV who are on effective antiretroviral therapy and have undetectable virus levels. The goal is to see if the drug can temporarily wake up dormant HIV hiding in cells, which could help researchers find new ways to target the viral reservoir. Participants will be closely monitored for changes in HIV activity and immune responses.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

oral methamphetamine

What this could lead to

If successful, this could identify new ways to flush out hidden HIV, potentially pointing toward strategies to reduce the viral reservoir.

What could go wrong

This is a very small, early-phase study with only 20 participants. The drug itself carries risks, and the findings may not translate into a cure or benefit for all people with HIV.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

HIV infectious disease methamphetamine dependence

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of California, San Francisco

    San Francisco, California, 94110, United States