Could a simpler HIV pill protect moms and babies?
NCT ID NCT07616739
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study will test a two-drug HIV pill (Dolutegravir/Lamivudine) in 210 pregnant women who have never taken HIV medication. The goal is to see if it controls the virus and prevents passing HIV to their babies. Participants will be compared to those on standard three-drug therapy. The study will also monitor side effects and birth outcomes.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Dolutegravir/Lamivudine (a two-drug HIV pill)
What this could lead to
If successful, this could show that a simpler two-drug regimen is safe and effective for pregnant women with HIV, reducing the risk of passing the virus to their babies.
What could go wrong
This is a Phase 4 study, so the drugs are already approved, but results may not apply to all populations. There is a risk of side effects or the two-drug combo being less effective than standard three-drug therapy.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Complexo do Hospital de Clínicas da UFPR/Ebserh
Curitiba, Pernambuco, 80430-000, Brazil
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Fundação Bahiana de Infectologia
Salvador, Estado de Bahia, 40110-160, Brazil
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Hospital General de Agudos Dr. Cosme Argerich
Ciudad Autónoma de Buenos Aires, Buenos Aires, C1155AHD, Argentina
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Hospital Geral de Nova Iguaçu
Nova Iguaçu, Rio de Janeiro, 26030-380, Brazil
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hospital Nacional Profesor Alejandro Posadas
El Palomar, Buenos Aires, B1684, Argentina
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hospital de Agudos J.A. Fernandez
Ciudad Autónoma de Buenos Aires, Buenos Aires, C1425AGP, Argentina
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hospital de Agudos Paroissien
Isidro Casanova, Buenos Aires, B1765, Argentina
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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RDSS - Ricardo Sobhie Diaz & Cia Solucoes Cientificas Ltda - Ricardo Diaz Scientific Solution
São Paulo, São Paulo, 04037-030, Brazil
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Sanatorio Güemes
Ciudad Autónoma de Buenos Aires, Buenos Aires, C1188AAF, Argentina
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Universidade Federal do Rio Grande do Norte
Natal, Rio Grande do Norte, 59075-070, Brazil
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact