HIGH GRADE GLIOMA
Clinical trials for HIGH GRADE GLIOMA explained in plain language.
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New hope for young brain cancer patients in groundbreaking trial
Disease control Not yet recruitingThis study is testing whether adding a new drug called ADI-PEG 20 to standard radiation and chemotherapy can help control aggressive brain tumors in children, teens, and young adults. The first part will find the safest dose, and the second part will see if the combination helps …
Matched conditions: HIGH GRADE GLIOMA
Phase: PHASE1, PHASE2 • Sponsor: Sabine Mueller, MD, PhD • Aim: Disease control
Last updated Apr 01, 2026 14:41 UTC
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New MRI-Guided radiation aims to target brain tumors more precisely
Disease control Not yet recruitingThis early-stage study is testing whether a more precise, higher-dose radiation treatment is safe for people with aggressive brain tumors. The treatment uses an advanced MRI-guided machine to target the tumor more accurately while trying to spare healthy brain tissue. Researchers…
Matched conditions: HIGH GRADE GLIOMA
Phase: PHASE1 • Sponsor: NYU Langone Health • Aim: Disease control
Last updated Mar 27, 2026 12:39 UTC
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New hope for kids with devastating brain cancers: targeted drug trial launches
Disease control Not yet recruitingThis study is testing whether a drug called tovorafenib can help children and young adults live longer after being diagnosed with aggressive brain tumors, including a type called DIPG. The drug is given after standard radiation treatment and targets tumors with specific genetic c…
Matched conditions: HIGH GRADE GLIOMA
Phase: PHASE2 • Sponsor: Nationwide Children's Hospital • Aim: Disease control
Last updated Mar 25, 2026 14:08 UTC
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Virus injected into brain to fight deadly childhood tumors
Disease control Not yet recruitingThis study is testing a new treatment for aggressive brain tumors that have come back or stopped responding to standard treatments in children and young adults. It involves a single injection of a modified virus (DNX-2401) directly into the tumor during a biopsy procedure. The ma…
Matched conditions: HIGH GRADE GLIOMA
Phase: PHASE2 • Sponsor: Clinica Universidad de Navarra, Universidad de Navarra • Aim: Disease control
Last updated Mar 23, 2026 15:15 UTC
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Scientists test 'Cancer-Killing Virus' for tough brain tumors
Disease control Not yet recruitingThis early-stage study is testing a new two-part treatment for aggressive brain cancer that has come back after standard therapy. It combines a specially engineered virus designed to infect and kill cancer cells with a drug that helps the immune system attack the tumor. The main …
Matched conditions: HIGH GRADE GLIOMA
Phase: PHASE1 • Sponsor: Beijing Bio-Targeting Therapeutics Technology Co., Ltd • Aim: Disease control
Last updated Mar 20, 2026 14:48 UTC
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Nose spray trial offers hope for kids with devastating brain tumors
Disease control Not yet recruitingThis early-stage study is testing the safety of an experimental nose spray called NEO100 in children and teenagers with aggressive brain tumors. The main goal is to find a safe dose and see if the medicine can successfully reach the tumor in the brain. Researchers will also check…
Matched conditions: HIGH GRADE GLIOMA
Phase: PHASE1 • Sponsor: Neonc Technologies, Inc. • Aim: Disease control
Last updated Mar 18, 2026 18:25 UTC
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New hope for deadly brain cancer: experimental drug enters human trials
Disease control Not yet recruitingThis early-stage trial is testing a new drug called LMP744 in adults whose aggressive brain cancer (glioblastoma) has returned after standard treatment. The main goal is to see if the drug can shrink tumors and slow the cancer's progression. Participants will receive the drug thr…
Matched conditions: HIGH GRADE GLIOMA
Phase: PHASE1, PHASE2 • Sponsor: National Institute of Neurological Disorders and Stroke (NINDS) • Aim: Disease control
Last updated Mar 16, 2026 15:23 UTC
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Glowing drug lights up brain tumors for surgeons
Knowledge-focused Not yet recruitingThis early study aims to see if a cancer drug (nivolumab) can be made to glow with a special dye, allowing doctors to see exactly where it goes in the brain during surgery for aggressive tumors called high-grade gliomas. The main goals are to check if this glowing version of the …
Matched conditions: HIGH GRADE GLIOMA
Phase: EARLY_PHASE1 • Sponsor: Eben Rosenthal • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:38 UTC