HIGH-GRADE GLIOMA
Clinical trials for HIGH-GRADE GLIOMA explained in plain language.
Never miss a new study
Get alerted when new HIGH-GRADE GLIOMA trials appear
Sign up with your email to follow new studies for HIGH-GRADE GLIOMA, keep track of the ones that matter, and come back to a personal dashboard instead of checking manually.
By submitting, you agree to our Terms of use
-
New hope for young brain tumor patients: experimental drug combo enters trials
Disease control Not yet recruitingThis study tests whether adding an experimental drug (ADI-PEG 20) to standard radiation and chemotherapy can help children, teens, and young adults with newly diagnosed high-grade glioma. About 97 participants will receive the drug combination to see if it is safe and delays tumo…
Matched conditions: HIGH-GRADE GLIOMA
Phase: PHASE1, PHASE2 • Sponsor: Sabine Mueller, MD, PhD • Aim: Disease control
Last updated May 17, 2026 03:15 UTC
-
New radiation strategy aims to safely boost brain tumor treatment
Disease control Not yet recruitingThis early-stage study tests a new way to give radiation to people with aggressive brain tumors (high-grade glioma). The goal is to see if it's safe to give higher doses to the most dangerous parts of the tumor using a special MRI-guided machine. Twenty adults with newly diagnose…
Matched conditions: HIGH-GRADE GLIOMA
Phase: PHASE1 • Sponsor: NYU Langone Health • Aim: Disease control
Last updated May 17, 2026 03:13 UTC
-
Virus and immunotherapy combo takes on deadly brain tumors
Disease control Not yet recruitingThis early-stage study tests a new treatment for people with recurrent high-grade glioma, a fast-growing brain cancer that has come back after standard therapy. The treatment combines a specially designed virus that targets and kills cancer cells with an immunotherapy drug that h…
Matched conditions: HIGH-GRADE GLIOMA
Phase: PHASE1 • Sponsor: Beijing Bio-Targeting Therapeutics Technology Co., Ltd • Aim: Disease control
Last updated May 17, 2026 03:11 UTC
-
New hope for kids with aggressive brain cancer: targeted drug trial launches
Disease control Not yet recruitingThis study tests a drug called tovorafenib in children and young adults (ages 1 to 39) who have been newly diagnosed with a fast-growing brain tumor (high-grade glioma or DIPG) that has a specific genetic change. The goal is to see if the drug can help them live longer by targeti…
Matched conditions: HIGH-GRADE GLIOMA
Phase: PHASE2 • Sponsor: Nationwide Children's Hospital • Aim: Disease control
Last updated May 13, 2026 16:00 UTC
-
New hope for brain cancer? experimental drug LMP744 targets recurrent glioblastoma
Disease control Not yet recruitingThis early-stage trial tests a new drug called LMP744 in 40 adults whose glioblastoma (a type of brain cancer) has come back after standard treatment. The drug is given through a vein for 5 days each month for up to a year. The goal is to see if it can shrink tumors or delay canc…
Matched conditions: HIGH-GRADE GLIOMA
Phase: PHASE1, PHASE2 • Sponsor: National Institute of Neurological Disorders and Stroke (NINDS) • Aim: Disease control
Last updated May 11, 2026 20:49 UTC
-
Nasal spray could deliver brain tumor treatment to kids
Disease control Not yet recruitingThis early-phase study tests a nasal spray called NEO100 in 12 children with specific, hard-to-treat brain tumors. The main goals are to check safety, find the best dose, and see if the drug reaches the tumor. It is a first step to see if this approach is safe enough for larger s…
Matched conditions: HIGH-GRADE GLIOMA
Phase: PHASE1 • Sponsor: Neonc Technologies, Inc. • Aim: Disease control
Last updated May 11, 2026 20:46 UTC
-
Virus injected into brain tumors shows promise for kids with no other options
Disease control Not yet recruitingThis study tests a treatment called DNX-2401, a virus that is injected directly into brain tumors to kill cancer cells. It is for children and young adults (up to age 39) whose high-grade brain tumors have come back or not responded to standard treatments. The goal is to see if t…
Matched conditions: HIGH-GRADE GLIOMA
Phase: PHASE2 • Sponsor: Clinica Universidad de Navarra, Universidad de Navarra • Aim: Disease control
Last updated Apr 30, 2026 15:49 UTC
-
New MRI technique could reveal invisible tumor infiltration
Knowledge-focused Not yet recruitingThis study tests whether special MRI scans can spot areas where brain tumors have spread into surrounding tissue, which standard scans miss. About 20 adults with suspected high-grade glioma will get advanced imaging before surgery. The goal is to create a map of tumor infiltratio…
Matched conditions: HIGH-GRADE GLIOMA
Sponsor: IRCCS Ospedale San Raffaele • Aim: Knowledge-focused
Last updated May 15, 2026 11:55 UTC