Nasal spray could deliver brain tumor treatment directly to Kids' tumors
NCT ID NCT06357377
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This early-phase trial tests a nasal spray called NEO100 (a purified natural compound) in 12 children with certain aggressive brain tumors. The goal is to see if it's safe, find the best dose, and check if the drug reaches the tumor. Participants will receive increasing doses, and tumor samples will be tested for the drug if surgery is already planned.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
NEO100 (a purified form of perillyl alcohol, a natural compound)
What this could lead to
If it works, this could point toward a new way to deliver treatment directly to brain tumors through the nose, potentially reducing side effects.
What could go wrong
This is a very early, small Phase 1b trial with only 12 participants, focused on safety and dosing. It may not show any benefit, and side effects are unknown.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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