Glowing dye could help surgeons spot hidden brain cancer

NCT ID NCT07609472

Not yet recruiting Disease control Sponsor: FluoGuide A/S Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase 2 trial tests a single dose of FG001, a fluorescent dye, in 76 adults with newly diagnosed high-grade glioma. The dye is given before surgery and glows under a special light, helping surgeons tell tumor from healthy tissue during removal. The study checks how well the dye works and how much tumor is removed, with follow-up for six months after surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: FG001 (a fluorescent dye that glows under near-infrared light to help surgeons see tumor tissue)
What this could lead to: If it works, FG001 could help surgeons remove more of the tumor during surgery, potentially improving outcomes for people with high-grade glioma.
What could go wrong: This is an early-phase trial with only 76 people, so results may not apply to everyone. The dye is new and may not clearly distinguish tumor from healthy tissue in all cases.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

astrocytoma, IDH-mutant, grade 2 ependymoma glioma IDH-mutant and 1p/19q-codeleted oligodendroglioma IDH-wildtype glioblastoma malignant glioma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HIGH-GRADE GLIOMA (WHO III-IV)

Contacts and locations

Locations

Dartmouth Hitchcock Medical Center

Lebanon, New Hampshire, 03567, United States
Huntsman Cancer Institute, University of Utah

Salt Lake City, Utah, 84112, United States
UPMC Presbyterian Hospital

Pittsburgh, Pennsylvania, 15213, United States
University of Miami

Miami, Florida, 33125, United States
University of Texas Medical Branch

Galveston, Texas, 77555, United States

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