HEMATOPOIETIC STEM CELL TRANSPLANTATION
Clinical trials for HEMATOPOIETIC STEM CELL TRANSPLANTATION explained in plain language.
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Can a bone drug save kids from fractures after transplant?
Disease control Recruiting nowThis early study tests whether giving a bone-strengthening drug called zoledronate soon after a stem cell transplant can safely prevent bone disease and fractures in children. About 20 children aged 5 to 18 who are at high risk for bone problems will receive the drug. The goal is…
Matched conditions: HEMATOPOIETIC STEM CELL TRANSPLANTATION
Phase: PHASE1 • Sponsor: Children's Hospital Medical Center, Cincinnati • Aim: Disease control
Last updated May 17, 2026 03:08 UTC
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Could a stem cell transplant tame VEXAS? new trial aims to find out
Disease control Recruiting nowThis study tests whether a stem cell transplant from a healthy donor can control VEXAS syndrome, a rare and severe autoinflammatory disease. Up to 54 adults aged 18-75 who have not responded to standard treatments will receive donor stem cells after chemotherapy and possibly radi…
Matched conditions: HEMATOPOIETIC STEM CELL TRANSPLANTATION
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 15, 2026 11:57 UTC
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Can a simple drug stop bleeding in stem cell patients?
Disease control Recruiting nowThis study tests whether etamsylate, a drug that helps blood clot, can prevent serious bleeding in people with very low platelet counts after a stem cell transplant. About 404 adults will receive either etamsylate or a placebo, and researchers will track who has a major bleed or …
Matched conditions: HEMATOPOIETIC STEM CELL TRANSPLANTATION
Phase: PHASE3 • Sponsor: First Affiliated Hospital of Zhejiang University • Aim: Disease control
Last updated May 15, 2026 11:57 UTC
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New drug aims to stop transplant rejection in stem cell patients
Disease control Recruiting nowThis early-phase study tests whether the drug emapalumab can prevent the body from rejecting a stem cell transplant in patients at high risk for graft failure. The study will enroll 20 participants and measure how well the drug works and how it behaves in the body. The goal is to…
Matched conditions: HEMATOPOIETIC STEM CELL TRANSPLANTATION
Phase: EARLY_PHASE1 • Sponsor: Children's Hospital Medical Center, Cincinnati • Aim: Disease control
Last updated May 15, 2026 11:56 UTC
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Could a lower dose of a transplant drug be better for blood cancer patients?
Disease control Recruiting nowThis study is for people with blood cancers like leukemia or lymphoma who need a stem cell transplant from a donor. After transplant, a drug called cyclophosphamide is given to prevent a serious side effect called graft-versus-host disease, but high doses can cause problems. The …
Matched conditions: HEMATOPOIETIC STEM CELL TRANSPLANTATION
Phase: PHASE1, PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 15, 2026 11:54 UTC
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New hope for leukemia patients: drug targets hidden cancer cells after transplant
Disease control Recruiting nowThis study tests a drug called inotuzumab ozogamicin in people with acute lymphoblastic leukemia (ALL) who still have tiny amounts of cancer cells (called minimal residual disease, or MRD) after a stem cell transplant. The goal is to see if the drug can clear these remaining cell…
Matched conditions: HEMATOPOIETIC STEM CELL TRANSPLANTATION
Phase: PHASE2 • Sponsor: Sheng-Li Xue, MD • Aim: Disease control
Last updated May 13, 2026 16:00 UTC
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New cell therapy aims to prevent painful mouth sores in stem cell transplants
Prevention Recruiting nowThis study tests whether a single infusion of amimestrocel, a cell therapy made from human umbilical cord cells, can prevent severe mouth and gut sores in patients receiving a stem cell transplant. About 22 adults will receive the infusion 1-2 days before their transplant. Resear…
Matched conditions: HEMATOPOIETIC STEM CELL TRANSPLANTATION
Phase: PHASE2 • Sponsor: The First Affiliated Hospital of Soochow University • Aim: Prevention
Last updated May 14, 2026 12:04 UTC
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Ancient heat therapy may shield bladder after bone marrow transplant
Prevention Recruiting nowThis study tests whether moxibustion, a traditional therapy that burns herbs near the skin, can prevent hemorrhagic cystitis (painful bladder bleeding) in 266 people receiving stem cell transplants for blood cancers or severe anemia. Participants are randomly assigned to standard…
Matched conditions: HEMATOPOIETIC STEM CELL TRANSPLANTATION
Phase: NA • Sponsor: Yi Zhang • Aim: Prevention
Last updated May 13, 2026 15:58 UTC
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Yoga therapy aims to ease depression in stem cell transplant patients across three continents
Symptom relief Recruiting nowThis study is testing a yoga program designed to fit different cultures for cancer patients who are in the hospital for a stem cell transplant. The goal is to see if the yoga program can help reduce symptoms of depression. About 60 adults from India, Tanzania, and the United Stat…
Matched conditions: HEMATOPOIETIC STEM CELL TRANSPLANTATION
Phase: NA • Sponsor: M.D. Anderson Cancer Center • Aim: Symptom relief
Last updated May 17, 2026 03:09 UTC
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New program aims to ease return to work after stem cell transplant
Symptom relief Recruiting nowThis study tests a new program called Work Support (WorkS) for people who have had a stem cell transplant and are worried about going back to work. The program includes sessions to help build confidence and address job concerns. Researchers want to see if the program is practical…
Matched conditions: HEMATOPOIETIC STEM CELL TRANSPLANTATION
Phase: NA • Sponsor: MGH Institute of Health Professions • Aim: Symptom relief
Last updated May 17, 2026 03:09 UTC
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Digital avatar aims to ease anxiety in stem cell transplants
Symptom relief Recruiting nowThis study tests whether a supportive digital avatar can help reduce anxiety and improve quality of life for cancer patients receiving a stem cell transplant as outpatients. About 90 adults will be randomly assigned to use the avatar program or receive usual care. The goal is to …
Matched conditions: HEMATOPOIETIC STEM CELL TRANSPLANTATION
Phase: NA • Sponsor: Victor Wang • Aim: Symptom relief
Last updated May 17, 2026 03:00 UTC
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Can planning ahead improve care for young transplant patients?
Knowledge-focused Recruiting nowThis study looks at whether having guided conversations about care preferences helps young adults (ages 18-39) who are about to receive a stem cell transplant, along with their caregivers. Participants will fill out questionnaires and have three talks with a study team member ove…
Matched conditions: HEMATOPOIETIC STEM CELL TRANSPLANTATION
Phase: NA • Sponsor: National Cancer Institute (NCI) • Aim: Knowledge-focused
Last updated May 15, 2026 11:55 UTC
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Scientists track stem cell transplants for years to unlock secrets
Knowledge-focused Recruiting nowThis study follows people who have had a stem cell transplant (and their donors) for many years after the procedure. Researchers want to learn about long-term side effects, how the transplanted cells change, and how to improve the body's ability to fight cancer. Participants will…
Matched conditions: HEMATOPOIETIC STEM CELL TRANSPLANTATION
Sponsor: National Cancer Institute (NCI) • Aim: Knowledge-focused
Last updated May 14, 2026 12:05 UTC
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10,000 transplant patients to reveal hidden heart risks
Knowledge-focused Recruiting nowThis study follows 10,000 people who have had a stem cell transplant to see how often heart problems occur afterward. Researchers will collect medical information and track events like heart attacks, strokes, and heart failure. The goal is to better understand and manage these ri…
Matched conditions: HEMATOPOIETIC STEM CELL TRANSPLANTATION
Sponsor: Peking University People's Hospital • Aim: Knowledge-focused
Last updated May 13, 2026 16:01 UTC
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Can what you eat after a stem cell transplant change your outcome?
Knowledge-focused Recruiting nowThis study looks at the nutritional health of 200 people who have had a stem cell transplant. Researchers will measure body composition, food intake, and blood protein levels over six months. The goal is to understand how nutrition affects recovery and long-term survival.
Matched conditions: HEMATOPOIETIC STEM CELL TRANSPLANTATION
Sponsor: The First Affiliated Hospital of Soochow University • Aim: Knowledge-focused
Last updated May 11, 2026 20:47 UTC
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New blood test could spot hidden infections in vulnerable transplant patients
Knowledge-focused Recruiting nowThis study is testing a new, advanced blood test to see if it can detect germs like bacteria and viruses in people receiving a stem cell transplant. Participants will have their blood drawn before the transplant and for six months after to look for signs of infection. The goal is…
Matched conditions: HEMATOPOIETIC STEM CELL TRANSPLANTATION
Sponsor: National Institutes of Health Clinical Center (CC) • Aim: Knowledge-focused
Last updated Apr 20, 2026 16:14 UTC