HEMATOPOIETIC STEM CELL TRANSPLANTATION
Clinical trials for HEMATOPOIETIC STEM CELL TRANSPLANTATION explained in plain language.
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Tailored drug dosing may cut infections after stem cell transplants
Disease control Recruiting nowThis study tests whether giving anti-thymocyte globulin (ATG) based on individual patient levels can reduce viral infections after stem cell transplants from unrelated donors. About 324 patients will receive either personalized or fixed doses of ATG. The goal is to find a dose th…
Matched conditions: HEMATOPOIETIC STEM CELL TRANSPLANTATION
Phase: PHASE4 • Sponsor: Daihong Liu • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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Could a lower dose of a transplant drug be better for blood cancer patients?
Disease control Recruiting nowThis study is testing whether a lower dose of the drug cyclophosphamide, given after a stem cell transplant, can prevent graft-versus-host disease (a common complication where donor cells attack the patient's body) while still being effective. The trial involves 260 adults with b…
Matched conditions: HEMATOPOIETIC STEM CELL TRANSPLANTATION
Phase: PHASE1, PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 27, 2026 13:07 UTC
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Could a stem cell transplant tame VEXAS syndrome?
Disease control Recruiting nowThis study tests whether a stem cell transplant from a donor can help people with VEXAS syndrome, a rare autoinflammatory disease. Participants receive donor stem cells after drugs to prepare their bone marrow. The goal is to see if the transplant can reverse symptoms and allow p…
Matched conditions: HEMATOPOIETIC STEM CELL TRANSPLANTATION
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 27, 2026 12:30 UTC
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Can a simple drug stop bleeding in stem cell patients?
Disease control Recruiting nowThis study tests whether etamsylate, a drug that helps blood clot, can prevent serious bleeding in people who have low platelets after a stem cell transplant. About 404 adults will receive either etamsylate or a placebo, and researchers will track who has a major bleed or dies wi…
Matched conditions: HEMATOPOIETIC STEM CELL TRANSPLANTATION
Phase: PHASE3 • Sponsor: First Affiliated Hospital of Zhejiang University • Aim: Disease control
Last updated Jun 27, 2026 09:09 UTC
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Bone drug tested to shield young transplant survivors from fractures
Disease control Recruiting nowThis early study tests whether giving a bone-strengthening drug called zoledronate soon after a stem cell transplant can safely prevent bone loss and fractures in children. Researchers will enroll 20 children aged 5 to 18 who are at high risk for bone problems. The goal is to see…
Matched conditions: HEMATOPOIETIC STEM CELL TRANSPLANTATION
Phase: PHASE1 • Sponsor: Children's Hospital Medical Center, Cincinnati • Aim: Disease control
Last updated Jun 27, 2026 09:00 UTC
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New drug aims to stop transplant rejection in High-Risk patients
Disease control Recruiting nowThis early-stage study tests whether a drug called emapalumab can prevent the body from rejecting a stem cell transplant. The study will include 20 patients who are at high risk for rejection. Researchers will also study how the drug works in the body to improve future treatments…
Matched conditions: HEMATOPOIETIC STEM CELL TRANSPLANTATION
Phase: EARLY_PHASE1 • Sponsor: Children's Hospital Medical Center, Cincinnati • Aim: Disease control
Last updated Jun 27, 2026 08:13 UTC
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New hope for leukemia patients: drug targets hidden cancer cells after transplant
Disease control Recruiting nowThis phase 2 trial tests the drug inotuzumab ozogamicin in 42 adults with B-cell acute lymphoblastic leukemia who have minimal residual disease (MRD) after a stem cell transplant. MRD means a few cancer cells remain undetectable by standard tests but can cause relapse. The drug a…
Matched conditions: HEMATOPOIETIC STEM CELL TRANSPLANTATION
Phase: PHASE2 • Sponsor: Sheng-Li Xue, MD • Aim: Disease control
Last updated Jun 27, 2026 07:58 UTC
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Immune-Guided drug timing could cut CMV prevention after transplant
Prevention Recruiting nowThis study tests a personalized approach to stopping the drug Letermovir, which prevents a common virus called CMV after a stem cell transplant. Instead of giving the drug for a fixed 100 days, doctors will use a blood test to see when a patient's own immune system has recovered …
Matched conditions: HEMATOPOIETIC STEM CELL TRANSPLANTATION
Phase: PHASE4 • Sponsor: WeiShi • Aim: Prevention
Last updated Jun 27, 2026 13:00 UTC
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Umbilical cord cell infusion aims to prevent painful mouth sores in transplant patients
Prevention Recruiting nowThis study tests whether a one-time infusion of amimestrocel, made from donated umbilical cord cells, can prevent severe mouth and gut sores in people receiving a stem cell transplant. About 22 adults will get the infusion before their transplant, and researchers will monitor for…
Matched conditions: HEMATOPOIETIC STEM CELL TRANSPLANTATION
Phase: PHASE2 • Sponsor: The First Affiliated Hospital of Soochow University • Aim: Prevention
Last updated Jun 27, 2026 12:07 UTC
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Ancient heat therapy tested to prevent post-transplant bladder pain
Prevention Recruiting nowThis study tests whether moxibustion, a traditional therapy that burns herbs near the skin, can prevent hemorrhagic cystitis (painful bladder inflammation) in 266 patients receiving stem cell transplants. Participants are randomly assigned to receive either standard care or stand…
Matched conditions: HEMATOPOIETIC STEM CELL TRANSPLANTATION
Phase: NA • Sponsor: Yi Zhang • Aim: Prevention
Last updated Jun 27, 2026 11:00 UTC
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Furry avatar may calm cancer patients during transplant
Symptom relief Recruiting nowThis study tests whether a friendly animated pet avatar on a tablet, guided by a human-AI team, can help reduce anxiety and improve quality of life for adults undergoing outpatient stem cell transplant for cancer. About 90 participants will be randomly assigned to receive the ava…
Matched conditions: HEMATOPOIETIC STEM CELL TRANSPLANTATION
Phase: NA • Sponsor: Victor Wang • Aim: Symptom relief
Last updated Jun 27, 2026 09:10 UTC
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Yoga may ease depression and anxiety during cancer transplants
Symptom relief Recruiting nowThis study is testing whether a yoga program designed to fit different cultures can help cancer patients who are getting a stem cell transplant. About 60 adults in India, Tanzania, and the United States will take part in up to 12 yoga sessions before and during their hospital sta…
Matched conditions: HEMATOPOIETIC STEM CELL TRANSPLANTATION
Phase: NA • Sponsor: M.D. Anderson Cancer Center • Aim: Symptom relief
Last updated Jun 27, 2026 09:08 UTC
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New program aims to ease job return after stem cell transplant
Symptom relief Recruiting nowThis study tests a new support program called WorkS for people who have had a stem cell transplant and are worried about going back to work. About 35 participants will receive coaching sessions to help them feel more confident and manage work-related challenges. The goal is to se…
Matched conditions: HEMATOPOIETIC STEM CELL TRANSPLANTATION
Phase: NA • Sponsor: MGH Institute of Health Professions • Aim: Symptom relief
Last updated Jun 27, 2026 08:05 UTC
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Scientists launch Decade-Long study to unlock secrets of stem cell transplants
Knowledge-focused Recruiting nowThis study follows people who have had a stem cell transplant (and their donors) for years after the procedure. Researchers want to understand long-term health effects, how the transplanted cells change, and how to improve the body's ability to fight cancer. Participants will hav…
Matched conditions: HEMATOPOIETIC STEM CELL TRANSPLANTATION
Sponsor: National Cancer Institute (NCI) • Aim: Knowledge-focused
Last updated Jul 02, 2026 05:00 UTC
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Can planning ahead ease the stress of stem cell transplants for young adults?
Knowledge-focused Recruiting nowThis study looks at whether having guided conversations about care preferences helps young adults (ages 18-39) who are about to receive a stem cell transplant, along with their caregivers. Participants will fill out questionnaires and have three talks with a study team member ove…
Matched conditions: HEMATOPOIETIC STEM CELL TRANSPLANTATION
Phase: NA • Sponsor: National Cancer Institute (NCI) • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:02 UTC
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Stem cell transplant study probes hidden toll on smell and taste
Knowledge-focused Recruiting nowThis study follows 70 people receiving a stem cell transplant for leukemia or myelodysplastic syndrome. Researchers will test their sense of smell, taste, mouth pain, and saliva production before and after the transplant. The goal is to understand how the treatment changes these …
Matched conditions: HEMATOPOIETIC STEM CELL TRANSPLANTATION
Sponsor: University of Oslo • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:28 UTC
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New DNA test could spot hidden infections in transplant patients
Knowledge-focused Recruiting nowThis study tests a new DNA/RNA scanning method to find hidden infections in people receiving stem cell transplants. Researchers will take blood samples before and up to 6 months after transplant to detect bacteria, viruses, fungi, or parasites. The goal is to see if this approach…
Matched conditions: HEMATOPOIETIC STEM CELL TRANSPLANTATION
Sponsor: National Institutes of Health Clinical Center (CC) • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:04 UTC
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Can what you eat after a stem cell transplant change your outcome?
Knowledge-focused Recruiting nowThis study tracks 200 patients who have had a stem cell transplant to understand their nutritional health. Researchers measure body composition, food intake, and blood protein levels over six months. The goal is to see if better nutrition leads to longer survival and fewer compli…
Matched conditions: HEMATOPOIETIC STEM CELL TRANSPLANTATION
Sponsor: The First Affiliated Hospital of Soochow University • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:02 UTC
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10,000 transplant patients to be tracked for hidden heart risks
Knowledge-focused Recruiting nowThis large observational study will follow 10,000 people who have had a stem cell transplant to see how often they develop heart problems like heart attacks, stroke, or heart failure. Researchers will collect medical data over time to better understand who is at risk and why. The…
Matched conditions: HEMATOPOIETIC STEM CELL TRANSPLANTATION
Sponsor: Peking University People's Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:11 UTC