Could a donor stem cell transplant stop VEXAS syndrome?

NCT ID NCT05027945

First seen Jan 06, 2026 · Last updated Jun 12, 2026 · Updated 25 times

Summary

This study tests whether a stem cell transplant from a healthy donor can control or reverse VEXAS syndrome, a rare and severe autoinflammatory disease. About 54 adults aged 18-75 whose standard treatments have failed will receive donor stem cells after chemotherapy and possibly radiation. The goal is to see if the transplant can eliminate disease symptoms without the need for ongoing steroids or other therapies.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • National Institutes of Health Clinical Center

    RECRUITING

    Bethesda, Maryland, 20892, United States

    Contact Phone: •••-•••-••••

Conditions

Explore the condition pages connected to this study.