Can gut bacteria help rebuild immunity after stem cell transplants?
NCT ID NCT07755319
First seen Aug 10, 2026 · Last updated Aug 13, 2026 · Updated 3 times
Summary
This trial explores whether transplanting gut bacteria from healthy donors can help restore the immune system in people who have weak immunity after a stem cell transplant. The study first observes immune recovery in patients to identify those with severe deficiency, then gives a short course of specially selected fecal microbiota capsules to a small group. The goal is to see if this approach is safe and feasible, and whether it can improve antibody production.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Fecal microbiota transplantation (FMT) capsules made from healthy donor stool, rich in propionate- and butyrate-producing bacteria.
- What this could lead to
- If successful, this could offer a new way to boost immune recovery after stem cell transplants, potentially reducing infections and other complications.
- What could go wrong
- This is an early-phase trial with a small number of participants, so results may not be conclusive. There are also risks of side effects, including infections or worsening of graft-versus-host disease.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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The First Affiliated Hospital of Soochow University
Suzhou, Jiangsu, 215006, China
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Other studies related to the condition(s) this trial covers.
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